This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami +9 more
wiley +1 more source
Emergence and expansion of dengue in Paltas: possible implications of the COVID-19 pandemic and climatic variations. [PDF]
Quintero B +4 more
europepmc +1 more source
From a parish square to John F. Kennedy Park. Evolution of the public space of Miraflores in Lima, Peru and the role of Ryszard de Jaxa Małachowski [PDF]
Barbara Olczak +7 more
openalex +1 more source
Abstract The rapid expansion of biodiversity data presents new opportunities to understand and forecast biosphere dynamics. However, disparate and dispersed data, taxonomic and geographic inconsistencies, pervasive quality issues, and a lack of reproducable workflows hinder synthesis, introduce biases and limit accurate assessment of biodiversity ...
Brian J. Enquist +38 more
wiley +1 more source
β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini +14 more
wiley +1 more source
Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017-2021: a retrospective study. [PDF]
Bovell AAN +5 more
europepmc +1 more source
Transformations in the parish of the Immaculate Heart of Mary in Otwock-Śródborów
Katarzyna Kulik
openalex +1 more source
Renaming in Adoption: Exploring Name Ambivalence in Adoptive Parents' Name Stories
ABSTRACT Names are central to identity, yet their role in adoption, where identity and family dynamics are complex, remains under‐researched. This article draws on findings from a qualitative study of names and adoption in England and Wales to examine adoptive parents' decisions about the first names of their children.
Jan Flaherty +3 more
wiley +1 more source
Trends in neighbourhood socioeconomic disadvantage and mortality disparities over three decades in Denmark. [PDF]
Foverskov E +3 more
europepmc +1 more source

