Results 151 to 160 of about 2,049,123 (312)

Speech in support of an Appalachian National Park

, 1902
This 4-page, typewritten draft is of a speech made by Chase Ambler at a convention held in October 1902, sponsored by the Appalachian National Park Association and the Asheville Board of Trade. The convention was successful with 1,500 people from various
Ambler, Chase P., 1865-1932;
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Resolution Endorsing the Appalachian National Park-Movement

, 2015
The Appalachian National Park Association drafted a number of petitions and resolutions favoring the establishment of a national forest reserve and/or a national park in the southern Appalachians.
Appalachian National Park Association;
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Appalachian National Park Association Newspaper Clippings, 1899-1902

, 2015
This is one of two notebooks assembled by the Appalachian National Park Association that includes documents and news clipping about the organization. The Appalachian National Park Association was formed in 1899 for the purpose of promoting the idea of a ...
Appalachian National Park Association;
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Measuring children's spatial accessibility to urban park green spaces. [PDF]

Sci Rep
Mohammadi A, Moghabeli R, Ahmed A, Bergquist R, Rocha J.   +4 more
europepmc   +1 more source

"Park City resident and U.S. Ski Team member Jeremy Nobis enjoys a day of Spring skiing at park City Ski Area. Park City celebrates Spring with the annual Snow-shine Festival."

, 1991
Black and white photograph of Park City resident and U.S. Ski Team member, Jeremy Nobis enjoys a day of Spring skiing at park City Ski Area; Park City celebrates Spring with the annual Snow-shine Festival, photo taken between 1991 and ...
Park City Ski Corp. / Lori Adamski Peek
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Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Correction: Consistent MRI pattern in ADSS1 myopathy with variable clinical presentations: A Korean cohort study. [PDF]

PLoS One
Kim SH, Choi Y, Park HJ, Hong JM, Choi YC.   +4 more
europepmc   +1 more source