Results 11 to 20 of about 9,196 (138)

Solanidine-derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients. [PDF]

Br J Clin Pharmacol
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Sarömba JA, Müller JP, Tupiec J, Roeth A, Kurt B, Kahles F, Laurentius T, Bollheimer C, Stingl JC, Just KS.   +9 more
europepmc   +3 more sources

Pain intensity and comorbid depressive symptoms in the general population: An analysis of the German Health Update Study (GEDA 2019/2020-EHIS). [PDF]

Eur J Pain
Abstract Background Pain and depressive symptoms often co‐occur, but the influence of pain intensity remains unclear. This study analyses the association between pain intensity and depressive symptoms in the general adult German population. Methods Data was obtained from the cross‐sectional German Health Update Study (GEDA 2019/2020‐EHIS).
Ahrend JN, Jobski K, Bantel C, Hoffmann F.   +3 more
europepmc   +2 more sources

Is sexual size dimorphism in walleye, Sander vitreus, a driver of seasonal movements in Lake Erie? [PDF]

J Fish Biol
Abstract Walleye (Sander vitreus) are a sexually dimorphic species in which females are larger than males in adulthood. Walleye can also exhibit sex‐ and population‐based differences in migration behavior. In Lake Erie, we used acoustic telemetry to test the prediction that female walleye exhibit larger broad‐scale movements than males during the ...
Bihun CJ, Faust MD, Kraus RT, MacDougall TM, Robinson JM, Vandergoot CS, Raby GD.   +6 more
europepmc   +2 more sources

Gravity inversion of deep-crust and mantle interfaces in the Three Gorges area

Geodesy and Geodynamics, 2012
To better understand the heterogeneity of deep-crust and mantle interfaces in the region of the Three Gorges, China, we used the Parker-Oldenburg iterative inversion method to invert existing Bouguer gravity data from the Three Gorges area (1 : 500000 ...
Wang Jian, Shen Chongyang, Ii Hui, Sun Shaoan, Xing Lelin   +4 more
doaj   +1 more source

Exogenous stimulation of Tanacetum vulgare roots with pipecolic acid leads to tissue-specific responses in terpenoid composition. [PDF]

Plant Biol (Stuttg)
Tissue‐specific changes in terpenoid patterns in tansy are induced by simulated induction of systemic acquired resistance using pipercolic acid. Abstract Tanacetum vulgare L., tansy, is a perennial plant with highly variable terpenoid composition, with mono‐ and sesquiterpenoids being the most abundant.
Rahimova H, Heinen R, Weber B, Weisser WW, Schnitzler JP.   +4 more
europepmc   +2 more sources

Depression in Chinese patients with type 2 diabetes: associations with hyperglycemia, hypoglycemia, and poor treatment adherence. [PDF]

, 2015
BackgroundWe hypothesize that depression in type 2 diabetes might be associated with poor glycemic control, in part due to suboptimal self-care. We tested this hypothesis by examining the associations of depression with clinical and laboratory findings ...
Chan, Juliana Cn, China Depression in Chinese Patients with Type 2 Diabetes (DD2) Study Group, Guo, Xiaohui, Ji, Linong, Jia, Weiping, Kong, Alice Ps, Li, Wenhui, Luk, Andrea Oy, Morisky, Donald E, Oldenburg, Brian, Sartorius, Norman, Ting, Rose Zw, Weng, Jianping, Wing, Yun-Kwok, Yang, Wenying, Zhang, Yuying   +15 more
core   +1 more source

Effective elastic thickness in the Central Andes. Correlation to orogenic deformation styles and lower crust high-gravity anomaly [PDF]

, 2018
Global studies have assessed the importance of elastic thickness (Te) on orogenic evolution, showing that the style and nature of upper crustal shortening are influenced by the inherited lithospheric strength. Thus, pioneer works have identified that the
Garcia, Hector Pedro Antonio, Gianni, Guido Martin, Lince Klinger, Federico Gustavo, Lupari, Marianela Nadia, Ruiz, Francisco, Sanchez, Marcos Ariel, Soler, Santiago Rubén   +6 more
core   +2 more sources

Multiple common garden experiments suggest lack of local adaptation in an invasive ornamental plant [PDF]

, 2011
Aims: Adaptive evolution along geographic gradients of climatic conditions is suggested to facilitate the spread of invasive plant species, leading to clinal variation among populations in the introduced range.
Binnekamp, D, Borot, Maxence, Denis de Senneville, B, Hautvast, G, Lagendijk, J J W, Maenhout, M, Moerland, M A   +6 more
core   +3 more sources

Moho Depth Derived from Gravity Data in the Taiwan Strait Area

Terrestrial, Atmospheric and Oceanic Sciences, 2010
We have constructed are gional Bouguer gravity anomaly map using marine and land data from Tai wan and the Chinese province of Fuchien, as well as SEASAT altimetry-de rived gravity data for the Tai wan Strait and its surrounding area.
Hsien-Hsiang Hsieh, Horng-Yuan Yen, Min-Hung Shih   +2 more
doaj   +1 more source

Content comparison of patient-reported outcome instruments used to measure burnout [PDF]

, 2015
The aim of this article is to compare the content of patient-reported outcome (PRO) burnout measures and to examine the degree of overlap between them and psychosocial difficulties (PSD) experienced by persons with burnout.
Cieza, A., Murid Al-Kudwah, H., Sabariego, C.   +2 more
core   +1 more source