Results 151 to 160 of about 9,647,508 (315)

Plasma level of alpha-synuclein oligomers as a biomarker for isolated rapid eye movement sleep behavior disorder diagnosis and progression: a prospective cohort study

Frontiers in Neurology
BackgroundAlpha-synuclein oligomers (o-α-syn) are pivotal in the pathogenesis of α-synucleinopathy. Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) serves as an early indicator of the disease, offering insights into disease mechanisms ...
Chao Ying, Chao Ying, Chao Ying, Chao Ying, Hui Zhang, Ting Wang, Yuan Li, Wei Mao, Songnian Hu, Songnian Hu, Songnian Hu, Songnian Hu, Lifang Zhao, Lifang Zhao, Yanning Cai, Yanning Cai, Yanning Cai, Yanning Cai, Yanning Cai   +18 more
doaj   +1 more source

Engineering Aging: Approaches to Model and Deconstruct Biological Complexity

Advanced Materials, EarlyView.
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar, Sunny Shinchen Lee, Thomas R. Cox, Yu Suk Choi, Steven G. Wise, Jennifer L. Young, Giselle C. Yeo, Khoon S. Lim   +7 more
wiley   +1 more source

Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results

Movement Disorders, 2008
C. Goetz, B. Tilley, S. Shaftman, G. Stebbins, S. Fahn, P. Martínez-Martín, W. Poewe, C. Sampaio, M. Stern, R. Dodel, B. Dubois, R. Holloway, J. Jankovic, J. Kulisevsky, A. Lang, A. Lees, S. Leurgans, P. LeWitt, D. Nyenhuis, C. Olanow, O. Rascol, A. Schrag, J. Teresi, J. J. van Hilten, Nancy Lapelle   +24 more
semanticscholar   +1 more source

Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson\u27s Disease Pathogenesis using Drosophila [PDF]

, 2016
Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain.
Tito, Antonio Joel, Jr., Zhang, Sheng
core   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source

E‐Textiles in Biomedicine: Real Time Sensing, Energy Storage, and Therapeutic Applications

Advanced Materials Interfaces, EarlyView.
E‐textiles merge electronics with fabrics to create intelligent, wearable systems for health, sports, and fashion. By embedding sensors, actuators, and conductive components, these textiles provide real‐time physiological monitoring. Complemented by flexible power sources including embedded batteries and energy‐harvesting technologies, e‐textiles ...
Shiva Sharma, Sudheesh K. Shukla, Atheesha Singh, Krishna K. Govender, Penny P. Govender   +4 more
wiley   +1 more source

MEMS‐Based Magnetoelectric Antennas for Wireless Power Transmission in Brain‐Implantable Devices

Advanced Materials Technologies, EarlyView.
Magnetoelectric (ME) antennas allow the minimization of the invasiveness of brain implantable devices, via powering wirelessly systems able to actuate neural tissue. In order to achieve the necessary power efficiency transmission, the choice of the materials and the system assembly is vital.
Laura Mazón‐Maldonado, Jungang Zhang, María Cerezo‐Sánchez, Mahdieh Shojaei Baghini, Roghaieh Parvizi, Hadi Heidari   +5 more
wiley   +1 more source

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Nature Neuroscience, 2000
R. Betarbet, T. Sherer, G. Mackenzie, M. Garcia-Osuna, A. Panov, J. Greenamyre   +5 more
semanticscholar   +1 more source

Clinical characteristics and reaction to dopaminergic treatment of drug-naïve patients with Parkinson's disease in central China: A cross sectional study [PDF]

, 2023
Weiqi Zeng, Yukai Wang, Ling Liu, Yi Wu, Yu Xu, Heng Zhai, Xiaoman Yang, Xuebing Cao, Yan Xu   +8 more
openalex   +1 more source

Nanophotonic Strategies for Chiral Biosensing: Nanoparticles, Metasurfaces, Magneto‐Optical, and Quantum Approaches

Advanced Photonics Research, EarlyView.
Recent advances in nanophotonics‐based chiral biosensing approaches are comprehensively reviewed, highlighting key trends, advantages, and limitations of each technology. Special attention is given to emerging strategies that exploit magneto‐optical and quantum plasmonic phenomena to enhance sensitivity down to the level of a few molecules, or even a ...
Jorge Ricardo Mejía‐Salazar
wiley   +1 more source