Results 241 to 250 of about 236,137 (343)

Revisiting eye blink in Parkinson's disease. [PDF]

open access: yesSci Rep
Vasudevan V   +7 more
europepmc   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

open access: yesAggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang   +4 more
wiley   +1 more source

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

open access: yesAggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang   +3 more
wiley   +1 more source

Bridging Mechanical Properties with Atomic Structures of Polymorphic α‐Synuclein Fibrils by Single‐Molecule Analysis and Molecular Dynamics Simulations

open access: yesAggregate, EarlyView.
α‐Synuclein fibrils exhibit distinct mechanical properties influencing their neurotoxicity and pathogenicity in synucleinopathies like Parkinson's disease. Combining optical tweezers and molecular dynamics simulations, this study builds the structure–mechanics relationships of wild‐type and two disease‐associated mutants E46K and A53T α‐Synuclein ...
Lulu Bi   +9 more
wiley   +1 more source

Presynaptic mechanisms of motor fluctuations in Parkinson’s disease: a probabilistic model [PDF]

open access: bronze, 2004
Raúl de la Fuente‐Fernández   +4 more
openalex   +1 more source

Multi‐Risk‐Level Sarcopenia‐Prone Screening via Machine Learning Classification of Sit‐to‐Stand Motion Metrics from Wearable Sensors

open access: yesAdvanced Intelligent Systems, EarlyView.
A machine learning approach utilizes micro inertial measurement units (μIMUs) for noninvasive sarcopenia screening through a sit‐to‐stand test. With 53 older participants wearing IMUs, 510 features are extracted across four motion phases. Five algorithms (support vector machine, K‐nearest neighbors, decision tree, linear discriminant analysis, and ...
Keer Wang   +11 more
wiley   +1 more source

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