Results 271 to 280 of about 236,137 (343)
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley +1 more source
Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland+6 more
wiley +1 more source
A Single‐Molecule Liposome Assay for Membrane Permeabilisation
Cell membrane disruption is associated with numerous diseases and underlies the activity of various antimicrobial agents. The rapid screening of compounds capable of disrupting or permeabilising biological membranes is essential to the search for new therapeutic drugs.
Krzysztof Marek Bąk+9 more
wiley +1 more source
Flavonoid‐Derived Probes for the Detection of Islet Amyloid Polypeptide Aggregates
Misfolding and aggregation of islet amyloid polypeptide (IAPP) has been implicated in Type‐2 diabetes (T2D), contributing to β‐cell dysfunction. We developed flavonoid‐based probes, F4 and MF1, for detecting IAPP fibrils. These probes showed improved fluorescence response, over 10‐fold higher binding affinity than Thioflavin T and enabled specific ...
Zijie Luo+6 more
wiley +1 more source
Cardiac autonomic function during exercise and incident Parkinson’s disease
van Duijvenboden S+13 more
europepmc +1 more source
Wearable Biomonitoring with 2D Carbon‐Based Nanocomposite Hydrogels
This review critically examines recent advancements in nanocomposite hydrogels, emphasizing the reinforcement mechanisms offered by 2D carbon‐based nanomaterials and exploring the various applications of these hydrogels. Furthermore, it discusses the current challenges and potential avenues for future development and practical implementation of ...
Ning Li+6 more
wiley +1 more source