Results 391 to 400 of about 9,453,577 (435)

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

, 1997
Parkinson's disease (PD) is a common neurodegenerative disorder with a lifetime incidence of approximately 2 percent. A pattern of familial aggregation has been documented for the disorder, and it was recently reported that a PD susceptibility gene in a ...
M. Polymeropoulos, C. Lavedan, E. Leroy, S. Ide, A. Dehejia, A. Dutra, B. Pike, H. Root, J. Rubenstein, R. Boyer, E. Stenroos, S. Chandrasekharappa, A. Athanassiadou, T. Papapetropoulos, W. Johnson, A. Lazzarini, R. Duvoisin, G. Iorio, L. Golbe, R. Nussbaum   +19 more
semanticscholar   +1 more source

Ageing and Parkinson's disease: substantia nigra regional selectivity.

Brain : a journal of neurology, 1991
The micro-architecture of the substantia nigra was studied in control cases of varying age and patients with parkinsonism. A single 7 mu section stained with haematoxylin and eosin was examined at a specific level within the caudal nigra using strict ...
J. Fearnley, A. J. Lees
semanticscholar   +1 more source

Parkinson’s disease and hospital admissions: frequencies, diagnoses and costs

Acta Neurologica Scandinavica, 2010
To evaluate the frequencies, causes and costs related to hospital admissions for patients with Parkinson's disease (PD) and controls.In a prospective cohort study, 108 patients with PD from a population-based prevalence study and 854 age- and sex-matched controls were followed regarding admissions to the Stavanger University Hospital over a period of ...
Corinna Vossius, Jan Petter Larsen, Jan Petter Larsen, Odd Bjarte Nilsen, Odd Bjarte Nilsen   +4 more
openaire   +3 more sources

Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications.

New England Journal of Medicine, 1988
Autografting of dopamine-producing adrenal medullary tissue to the striatal region of the brain is now being attempted in patients with Parkinson's disease.
S. Kish, K. Shannak, O. Hornykiewicz
semanticscholar   +1 more source

Expression of LIF and LIF receptor beta in Alzheimer’s and Parkinson’s diseases

Acta Neurologica Scandinavica, 2010
Signaling through the leukemia inhibitory factor (LIF) receptor (LIFR) is crucial for nervous system development. There are few studies concerning the expression of LIF and LIFR in normal and degenerating adult human brain.To study the expression of LIF and LIFR in Alzheimer's disease (AD), Parkinson's disease (PD), and control brains.LIF and LIFR mRNA
Matias Röyttä, Merja Soilu-Hänninen, Juha O. Rinne, Veijo Hukkanen, Eeva Broberg, P Mattila   +5 more
openaire   +3 more sources

Staging of brain pathology related to sporadic Parkinson’s disease

Neurobiology of Aging, 2003
H. Braak, K. Tredici, U. Rüb, R. Vos, Ernst N. H. Jansen Steur, E. Braak   +5 more
semanticscholar   +1 more source