Results 241 to 250 of about 119,702 (338)
Annals of Neurology, EarlyView.Objective Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post‐mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive‐diagnosed with idiopathic PD have an alternative post ...
Lazzaro di Biase +2 more
wiley +1 more source
Evaluation of retinal microvascular changes with OCT-A in Parkinson disease and essential tremor. [PDF]
Medicine (Baltimore)Erdem M +4 more
europepmc +1 more source
Annals of Neurology, EarlyView.Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino +13 more
wiley +1 more source
Intravenous arachnoid granulation hypertrophy in patients with Parkinson disease. [PDF]
NPJ Parkinsons DisLeguizamon M +10 more
europepmc +1 more source
Cyclic Alternating Pattern Dynamics in Individuals at Risk for Developing Parkinson's Disease
Annals of Neurology, EarlyView.Objective The objective of this study was to investigate the differences in cyclic alternating patterns (CAP) metrics, a non‐rapid eye movement (NREM) sleep physiological rhythm, among recently diagnosed patients with Parkinson's disease (PD), and individuals at high and low risk for developing PD based on genetic and prodromal risk.
Andrew Dagay +5 more
wiley +1 more source
Hospice Use Among Medicare Beneficiaries With Parkinson Disease and Dementia With Lewy Bodies.
JAMA Netw OpenBock M +7 more
europepmc +1 more source
Pro-Oxidative and Inflammatory Actions of Extracellular Hemoglobin and Heme: Molecular Events and Implications for Alzheimer's and Parkinson Disease. [PDF]
Biomol Ther (Seoul)Campomayor NB, Kim HJ, Kim M.
europepmc +1 more source
Blood DDIT4 and TRIM13 Transcript Levels Mark the Early Stages of Machado–Joseph Disease
Annals of Neurology, EarlyView.Objective An abundance of select transcripts and proteins has been found to be dysregulated in blood samples of Machado–Joseph disease (MJD) carriers. Here, we aimed to: (1) identify blood transcriptional changes as potential biomarkers of MJD; (2) correlate levels of differentially expressed blood transcripts with MJD carriers features; and (3 ...
Ana F. Ferreira +10 more
wiley +1 more source
Angewandte Chemie, EarlyView.The discovery of LIBX‐A401, a potent and selective ACSL4 inhibitor derived from rosiglitazone is reported. HDX‐MS reveals that LIBX‐A401 stabilizes the ACSL4 C‐terminus and alters the fatty acid (FA) gate domain. Consistently, photoaffinity labeling, molecular dynamics, and mutagenesis identify key binding residues within the FA pocket.
Darius Mazhari Dorooee +19 more
wiley +2 more sources