Results 301 to 310 of about 119,702 (338)

Genetics of Parkinson's disease and parkinsonism

Annals of Neurology, 2006
AbstractUntil 10 years ago, conventional wisdom held that Parkinson's disease was not a genetic disorder. Since that time, there have been a plethora of genetic findings, culminating in the cloning of several genes that derive from the loci given the nomenclature PARK1‐PARK12 (OMIM 168600).
Andrew B. Singleton, Huaiban Cai, John Hardy, Mark R. Cookson, Katrina Gwinn-Hardy   +4 more
openaire   +3 more sources

Bradysomnia in Parkinson’s disease

Clinical Neurophysiology, 2016
Polysomnography studies in Parkinson's disease (PD) patients show altered sleep microstructure with decreased level of arousability, indicating impaired sleep-wake dynamics in PD. The aim of this study was to investigate dynamical aspects of sleep EEG in PD as compared to healthy controls.In this retrospective, controlled study, we applied a previously
Imbach, Lukas L, Sommerauer, Michael, Poryazova, Rositsa, Werth, Esther, Valko, Philipp O, Scammell, Thomas E, Baumann, Christian R   +6 more
openaire   +2 more sources

Identification of parkinsonism and Parkinson's disease

Drugs of Today, 2002
Parkinson's disease is a common movement disorder associated with considerable disability. The clinical syndrome of parkinsonism is based on the presence of core clinical features of rest tremor, bradykinesia, rigidity and impaired postural reflexes or gait.
openaire   +3 more sources

Parkinson's disease

The Lancet, 2009
Parkinson's disease is a common progressive bradykinetic disorder that can be accurately diagnosed. It is characterised by the presence of severe pars-compacta nigral-cell loss, and accumulation of aggregated alpha-synuclein in specific brain stem, spinal cord, and cortical regions. The main known risk factor is age.
Andrew J, Lees, John, Hardy, Tamas, Revesz   +2 more
openaire   +5 more sources

James Parkinson: Parkinson's Disease

Journal of Perioperative Practice, 2013
Parkinson's disease is a condition that anyone with a modicum of medical knowledge can recognise in the street - as indeed how it was studied by James Parkinson himself. Its three characteristic features are: 1. Increase in the tone of the voluntary muscles (rigidity). 2. Slowness of movement (bradykinesis). 3.
openaire   +2 more sources

Dementia in Parkinson Disease

Journal of Neurology, 1986
Advanced Parkinson's disease (PD) is frequently associated with dementia. The pathogenesis of this dementia is complex, related to deficiency of several biogenic amines and cortical Lewy body deposition, as well as co-existent age-related brain changes, both of the Alzheimer's type and vascular.
openaire   +3 more sources

Parkinson disease

2018
Parkinson disease (PD) is a complex, multisystem disorder with both neurologic and systemic nonmotor manifestations. It is neurodegenerative in nature in which disordered balance, gait, and falls are universal problems that can be present at initial diagnosis, and which progress over time.
Samuel D, Kim, Natalie E, Allen, Colleen G, Canning, Victor S C, Fung   +3 more
openaire   +2 more sources

Parkinson's disease, Parkinsonism and aging

Archives of Gerontology and Geriatrics, 2002
NICITA MAURO, Vittorio, BASILE, Giorgio, MENTO A, EPIFANIO A, MARTINO, GABRIELLA, MORGANTE, Letterio   +5 more
openaire   +3 more sources

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
Mitchell H Rosner, Kenar D Jhaveri, Mark A Perazella   +2 more
exaly  

Parkinson's disease

The Lancet, 2005
Druin, Burch, Fintan, Sheerin
openaire   +2 more sources