Scientific opinion on the modification of the terms of authorisation of the preparations of <i>Lactiplantibacillus plantarum</i>CNCM I-3235, <i>Pediococcus acidilactici</i>CNCM I-3237, <i>Pediococcus pentosaceus</i>NCIMB 12455, <i>Acidipropionibacterium acidipropionici</i>CNCM I-4661 and <i>Lentilactobacillus hilgardii</i>CNCM I-4785 as feed additives for all animal species (Danstar Ferment AG). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
europepmc +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
A qualitative investigation of stakeholders' perceptions of social prescribing for families with infants through the lens of a creative play on prescription programme for 0-2-year-olds and their carers. [PDF]
Davis PE, Retzler J, Kola-Palmer S.
europepmc +1 more source
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Safety evaluation of the food enzyme thermolysin from the non-genetically modified <i>Anoxybacillus caldiproteolyticus</i> strain DP-Fzj32. [PDF]
EFSA Panel on Food Enzymes (FEZ) +19 more
europepmc +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
EUPopLink Country report - Romania. [PDF]
Negrea-Busuioc E, Stancea A.
europepmc +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Evaluation of confirmatory data following the Article 12 MRL review for isoxaben. [PDF]
European Food Safety Authority (EFSA) +18 more
europepmc +1 more source
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source

