Results 111 to 120 of about 197,825 (332)

Eclectisch en toch nieuw. De uitvinding van het Belgisch parlement in 1830-1831

open access: yesBMGN: Low Countries Historical Review, 2005
Eclectic yet still new. The creation of the Belgian parliament in 1830-1831 The Belgian Constitution of 1831 consisted mainly of clauses borrowed from older constitutions.
H. De Smaele
doaj   +1 more source

A Citizens Compact: Reaching out to the Citizens of Europe. CEPS EPIN Working Papers No. 14, 1 September 2005 [PDF]

open access: yes, 2005
[Executive Summary]. How can the deadlock after the ‘no’ to the European Constitutional Treaty in France and the Netherlands be overcome? What should be the aim of the ‘period of reflection’ that has been agreed by the European Council?
Crum, Ben   +12 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A SWIFT change after Lisbon? The European Parliament's salience in the media [PDF]

open access: yes, 2011
The case of SWIFT (Society for Worldwide Interbank Financial Telecommunication) has generated a heated discussion between the European Parliament, the Council, and the Commission concerning the data exchange via bank transfers between the EU and the US ...
Gattermann, Katjana
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Virtues in Political Practice: Insights From an Interview Study With Swedish Parliamentarians

open access: yesPolitics and Governance
Which virtues, and why these, are most important for politicians? While philosophical discussions on virtues in politics are extensive, empirical investigations into the virtues politicians themselves value remain limited. This article addresses this gap
Joel Martinsson
doaj   +1 more source

The Relationship between Economic Performance and the Rise of \u2018Unholy Alliances\u2019 in the European Union [PDF]

open access: yes, 2018
This article investigates the phenomenon of \u2018unholy alliances\u2019: grand coalitions and ideologically-incoherent coalitions in the EU. In the last decade, these types of government majorities have proliferated, even in countries that have not ...
Morini, Marco
core   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The story of the first ‘yellow card’ shows that national parliaments can act together to influence EU policy [PDF]

open access: yes, 2015
The Treaty of Lisbon introduced a so called ‘yellow card’ system under which national parliaments can force the European Commission to review an EU legislative proposal if one third of parliaments issue an objection. As Ian Cooper writes, the yellow card
Cooper, Ian
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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