Results 81 to 90 of about 33,596 (238)

Clinical Features of Cellular Senescence Pathways in Severe Asthma

open access: yesAllergy, EarlyView.
In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.
Woo‐Jung Song   +122 more
wiley   +1 more source

Coinvolgere una città - esaltare una dinastia. Le pubbliche celebrazioni per lo sposalizio di Ferdinando I di Borbone e Maria Amalia d’Asburgo (1769) nelle carte dell’Archivio di Stato di Parma

open access: yesRicerche di S/Confine
Nel 1769, a Parma, si svolsero le nozze di Ferdinando I di Borbone con Maria Amalia d’Asburgo. Comparando la relazione ufficiale delle feste pubbliche, orchestrate dal segretario di stato Guillaume-Léon Du Tillot, con le notizie tramandate da documenti ...
Claudio Passera
doaj  

Longer Asthma Duration Is Associated With Elevated Non‐T2 Sputum Biomarkers and Reduced T2 Inflammation in Severe Asthma

open access: yesAllergy, EarlyView.
Longer asthma duration is associated with increased airway non‐T2 inflammation and reduced airway and systemic T2 inflammation. Sputum CXCL9 is independently associated with duration and may predict a reduced poor response to anti‐IL‐4Rα therapy. Airway sampling and combined T2 and non‐T2 targeted strategies may be needed in long‐standing asthma. CXCL9,
Freda Yang   +298 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin   +30 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno   +19 more
wiley   +1 more source

The Complex Interplay Between Sleep and Healthy Aging: A Scoping Review

open access: yesNature and Science of Sleep
Nicola Luigi Bragazzi,1 Carlotta Mutti,2,3 Pietro Luca Ratti,4,5 Alberto Sardella,6 Maria C Quattropani,6 Raffaele Lodi,7,8 Fabio Pizza,9,10 Francesco Biscarini,9,10 Dario Bottignole,2,3 Marco Salvi,3,11 Marcello Maggio,3,11 Liborio Parrino,2,3 Giuseppe ...
Bragazzi NL   +13 more
doaj  

Witnessing Racial Discrimination Mobilizes Intra‐Minority Allyship: Egalitarian Beliefs, Not Identification With All Humanity, Shape Who Acts

open access: yesJournal of Applied Social Psychology, EarlyView.
ABSTRACT Witnessing racial discrimination can be a powerful moral encounter, yet little is known about how minority group members respond when the targets are other minorities, such as Black people. Across three studies, we examined when witnessing discrimination predicts intra‐minority allyship with Black people. In Study 1a (N = 155 Ukrainians in the
Maria Chayinska   +4 more
wiley   +1 more source

Management of Periodontal Abscesses and Endodontic‐Periodontal Lesions—A Systematic Review

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the management of periodontal abscesses and endodontic‐periodontal lesions (EPLs). Methods Seven focused questions addressed outcomes such as pocket depth (PD), bleeding on probing (BOP), tooth loss or ovoid elevation. The literature search covered three electronic databases and manual sources for intervention studies.
Henrik Dommisch   +5 more
wiley   +1 more source

La nouvelle médiévale au prisme de l’intersectionnalité : l’histoire d’Alibech et Rustico (Décaméron III, 10)

open access: yesPerspectives Médiévales
This article proposes to study the genre of the medieval novella through the lens of intersectionality. This notion, from the fields of law and social sciences, aims to highlight the interconnected nature of relations of domination.
Giulia Parma
doaj   +1 more source

Outcome Measures and ID‐COSM Reporting Standards in Alveolar Ridge Augmentation: A Systematic Review of Clinical Trials

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate outcome measures in clinical studies on alveolar ridge augmentation (ARA) and map them to the Implant Dentistry Core Outcome Set and Measurement (ID‐COSM) framework and the Food and Drug Administration (FDA) terminology. Methods A systematic search was carried out across four databases through June 2025.
Khushboo Kalani   +6 more
wiley   +1 more source

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