Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. [PDF]
AIMS: More than half of infants exposed to opioids in utero develop neonatal abstinence syndrome (NAS) of severity to require pharmacological therapy. Current treatments are associated with prolonged hospitalization.
Abdel-Latif +26 more
core +2 more sources
Interleukin-6 blockade raises LDL via reduced catabolism rather than via increased synthesis: a cytokine-specific mechanism for cholesterol changes in rheumatoid arthritis [PDF]
Objectives Patients with rheumatoid arthritis (RA) have reduced serum low-density lipoprotein cholesterol (LDL-c), which increases following therapeutic IL-6 blockade. We aimed to define the metabolic pathways underlying these lipid changes.
Caslake, Muriel +6 more
core +1 more source
Essai d'analyses quantitative, qualitative et biogéographique de la flore fu Bou-Naceur (Moyen-Atlas oriental, Maroc) [PDF]
Essai d'analyses quantitative, qualitative et biogéographique de la flore du Bou-Naceur (Moyen-Atlas oriental, Maroc). En l'absence d'étude exhaustive sur le Moyen-Atlas oriental, la flore de cette région est restée assez mal connue par rapport au reste ...
Rahou, Abdelilah
core +4 more sources
Gentian violet for pyoderma gangrenosum: a retrospective chart review [PDF]
Pyoderma gangrenosum is a rare autoinflammatory skin disease. Treatment is multifactorial, addressing inflammation, pain, underlying disease, if present, and the wound.
Cline, A +6 more
core
Summary Multiple myeloma (MM) is a clonal malignancy of plasma cells characterized by frequent relapse and therapeutic resistance. G protein‐coupled receptor class C group 5 member D (GPRC5D) has emerged as a promising immunotherapeutic target due to its high and selective expression in MM cells and minimal presence in normal tissues.
Xueting Wang +3 more
wiley +1 more source
Is the combination of cryotherapy and topical timolol solution superior to cryotherapy alone in the treatment of epidermal growth factor receptor inhibitor-induced paronychia? A double-blinded, left-to-right comparison, randomized controlled trial [PDF]
Ya‐Wen Hsiao, Yu‐Chen Huang
openalex +1 more source
Amivantamab Plus Chemotherapy in Japanese Patients With EGFR Exon 20 Insertions NSCLC
This subpopulation analysis of the open‐label phase 3 trial (PAPILLION) evaluates the efficacy and safety of amivantamab–chemotherapy versus chemotherapy among Japanese patients with locally advanced or metastatic NSCLC with EGFR Exon 20ins mutation. Efficacy and safety results in this Japanese subpopulation were consistent with those in the overall ...
Satoru Kitazono +18 more
wiley +1 more source
Chemotherapy and skin reactions. [PDF]
BACKGROUND:New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a ...
Bianca D +6 more
core +1 more source
Doxycycline Prophylaxis in Adolescent Patients Treated With MEK Inhibitors
ABSTRACT Mitogen‐activated protein kinase inhibitors (MEKi) are used to treat various conditions, including plexiform neurofibromas, brain tumors, and cancers. Our study aimed to determine whether doxycycline prophylaxis could reduce the frequency and/or severity of acneiform eruptions and paronychia, common side effects of MEKi.
Faith Cormier +2 more
wiley +1 more source

