Results 41 to 50 of about 6,563 (147)

Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Autoimmune disorder patients are vulnerable to cytomegalovirus (CMV) infections, which can present with symptoms that mimic flare‐ups of the underlying disease. We present two cases: a 44‐year‐old woman with systemic lupus erythematosus and a 55‐year‐old man with sarcoidosis, both of whom developed unusual manifestations linked to CMV infection ...
Elaheh Karimi, Zahra Moradi, Somayeh Soroureddin, Ozra Nouri, Zahra Tamartash, Hoda Kavosi   +5 more
wiley   +1 more source

Trametinib therapy for children with neurofibromatosis type 1 and life‐threatening plexiform neurofibroma or treatment‐refractory low‐grade glioma

Cancer Medicine, 2021
Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at British Columbia ...
Rebecca Ronsley, Celine D. Hounjet, Sylvia Cheng, Shahrad Rod Rassekh, Walter J. Duncan, Christopher Dunham, Jane Gardiner, Arvindera Ghag, Jeffrey P. Ludemann, David Wensley, Wingfield Rehmus, Michael A. Sargent, Juliette Hukin   +12 more
doaj   +1 more source

Histopathologic features of selumetinib‐induced paronychia in a child with neurofibromatosis type 1

JEADV Clinical Practice
We report a 4‐year‐old girl developing therapy refractory paronychia induced by selumetinib, an oral selective inhibitor of mitogen‐activated protein kinase 1/2 prescribed for a large submandibular plexiform neurofibroma. Although this cutaneous reaction
P. Borgia, J. Ferro, G. Piccolo, P. Striano, V. G. Vellone, G. Viglizzo, M. C. Diana   +6 more
doaj   +1 more source

Retronychia: Surgical treatment and postoperative care

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Galina Balakirski, Alexander Kreuter, Silke C. Hofmann, Thorsten Neubert, Alexandros Paschos   +4 more
wiley   +1 more source

Cutaneous Toxicities Associated With Amivantamab in Patients With Non‐Small Cell Lung Cancer: A Systematic Review

International Journal of Dermatology, EarlyView.
Ioannis‐Alexios Koumprentziotis, Aikaterini Bakella, Antonis Tsimpidakis, Alexander Stratigos, Vasiliki Nikolaou   +4 more
wiley   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, Volume 48, Issue 1, Page 160-174, January 2026.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti, Joseph M. Curry, Jennifer Johnson, Michael Kwon, Shirley Y. Su, Francisco Civantos, Coral Olazagasti, Joseph Valentino, Susanne M. Arnold, R. Bryan Bell, Michael K. Gibson, Kyle Mannion, Kathryn M. Van Abel, Katharine A. Price, Haiying Dong, Amy H. Thorne, Toshiaki Suzuki, Ann M. Gillenwater   +17 more
wiley   +1 more source

The Study of the Effect of Terbinefine on the Nail and Skin Dermatomycoses

پزشکی بالینی ابن سینا, 1995
In this research, the effect of terbinefine oral and topical on the nail and skin dermatomycoses and chronic candida paronychia was studied. The patients were divided into three groups, each group was  studied with one kind of protocole, in this ...
Farhad Malekzad, Elaheh Ghaderi, Parviz Tousi   +2 more
doaj  

Epidemiological and antibiotic susceptibility pattern of bacterial paronychial infection

Journal of the Pakistan Medical Association
Objective: To identify the bacterial aetiology of paronychia, and assess the antibiotic resistance patterns of the isolated pathogens. Method: The cross-sectional cohort study was conducted from December 1, 2021, to December 31, 2022, at the ...
Bilal Javed, Muhammad Kamran Taj, Masroora Ali Khan, Aroosa Akram   +3 more
doaj   +1 more source

A Nonparametric Population Pharmacokinetic Model of Selumetinib in Pediatric Patients Diagnosed With Neurofibromatosis‐I or Plexiform Neurofibromas

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT A twice‐daily administration of oral selumetinib (SLT) in the fasted state is the only approved pharmaceutical option for treating inoperable neurofibromatosis type I (NF‐1) and plexiform neurofibromas (PN). In children, exposure to SLT is highly variable, and fasting presents a substantial burden.
Zoltán Köllő, Janka Kovács, Michael N. Neely, Barna Vásárhelyi, Edit Brückner, Attila J. Szabo, Miklós Garami, Gellért Balázs Karvaly   +7 more
wiley   +1 more source

The Inhibitory Effects of Zinc Oxide Nanoparticles on Clinical Isolates of Malassezia in Dogs

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Zinc oxide nanoparticles inhibit the growth and virulence of Malassezia pachydermatis clinical isolates from dogs. ZnO NPs exhibit potent fungicidal activity at low concentrations (MIC 3.90–7.81 ppm) and significantly downregulate the expression of Phospholipase A2 and Aspartyl proteinase genes, key virulence factors. This demonstrates the potential of
Alaleh Vazifehdust, Donya Nikaein, Matin Mozafari, Masoomeh Khanipour Machiani, Shahram Jamshidi, Javad Malakootikhah   +5 more
wiley   +1 more source