Results 91 to 100 of about 19,638 (219)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

open access: yesHead &Neck, Volume 48, Issue 9, Page 2364-2376, September 2026.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam   +10 more
wiley   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

open access: yesHead &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan   +12 more
wiley   +1 more source

Evaluation of Systemic Inflammatory Markers in Predicting Malignancy in Parotid Gland Tumors

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3783-3790, September 2026.
Preoperative systemic inflammatory indices may assist in distinguishing benign from malignant parotid tumors. In this cohort of 259 patients undergoing parotidectomy, malignant tumors were associated with higher neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) values, as well as larger tumor size and older age.
Ozcelik Erdem Rukiye   +3 more
wiley   +1 more source

Intraparotid lymph node tuberculosis

open access: yesB-ENT, 2008
Intraparotid lymph node tuberculosis. Problem: Parotid gland Mycobacterial infection is a rare disease that causes parotid swelling without disease-specific manifestations.
M. Archontaki   +4 more
doaj   +2 more sources

Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3791-3796, September 2026.
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen   +3 more
wiley   +1 more source

Transoral Robotic Resection of Pediatric Tongue Base Mucoepidermoid Carcinoma

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 4043-4048, September 2026.
Transoral robotic surgery (TORS) offers a precise, minimally invasive approach for the management of rare pediatric tongue base malignancies. Intraoperative visualization demonstrates accurate tumor delineation and controlled resection, while postoperative findings confirm effective oncologic clearance with preservation of surrounding structures.
Krisztina Somogyvári   +4 more
wiley   +1 more source

AI‐assisted VMAT planning incorporating deep learning‐based dose prediction for head and neck cancer: feasibility of quality standardization and human intervention for irregular cases

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Volumetric‐modulated arc therapy (VMAT) represents a standard of care for head and neck cancer (HNC). However, treatment plan quality depends heavily on the planner's expertise, thereby challenging the standardization of treatment quality.
Seiji Tomori   +2 more
wiley   +1 more source

Image‐based evaluation of a commercial AI synthetic CT generator for brain and prostate MR‐only radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Synthetic CTs (sCT) were developed to provide electron density information for MR‐only treatment planning. Some AI‐based sCT generators have received FDA‐clearance and better capture tissue heterogeneity through voxel‐wise mappings to improve image guidance and dose calculation.
Morgan Aire   +7 more
wiley   +1 more source

De Novo Polymorphous Adenocarcinoma of Parotid Gland – A Rare Case Report

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Polymorphous adenocarcinoma (PAC), previously termed as polymorphous low-grade adenocarcinoma, is an indolent malignant neoplasm of the minor salivary glands and is most commonly located in the palate, but is rarely described in major salivary glands ...
Subramanian K. Selvi   +2 more
doaj   +1 more source

Initial experience of clinical implementation of an Online Simulation‐free CBCT‐based Adaptive Radiotherapy (OSCAR) workflow for palliative and urgent treatment indications

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background The current standard radiotherapy treatment planning workflow typically requires several hours to days, during which patients must wait before treatment can be initiated. In certain oncological situations, however, treatment should commence as soon as possible.
Robert Schindhelm   +14 more
wiley   +1 more source

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