Results 51 to 60 of about 61,121 (211)

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

THE IMPORTANCE OF EARLY CARDIOVERSION OF PAROXYSMAL ATRIAL FIBRILLATION

Zdravniški Vestnik, 2002
Background. Atrial fibrillation is one of the most common arrhythmias. There is a traditional division by time course into acute and chronic forms. The classification of acute forms is unsatisfactory.
Franc Verovnik
doaj  

Is Stroke risk analysis (SRA) a reliable method for predicting atrial fibrillation? A systematic review.

PLoS ONE
IntroductionAtrial fibrillation is responsible for a considerable number of cases of cardioembolism, accounting for 17% to 30% of the etiologies of all strokes.
Rafael Alessandro Ferreira Gomes, Michel Pompeu Barros de Oliveira Sá, Marcela Vasconcelos Montenegro, Ludmila Cristina Camilo Furtado, José Henrique Cardoso Ferreira da Costa, Daniel Barros Coutinho, Johnnes Henrique Vieira Silva, Dário Celestino Sobral Filho   +7 more
doaj   +1 more source

Catheter Ablation: Evolution and Efficiencies

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Longstanding Persistent Atrial Fibrillation Ablation: How Do You Perform It?

Journal of Cardiac Arrhythmias, 2020
Longstanding-persistent atrial fibrillation is one of the most challenging arrhythmias to treat. While radiofrequency catheter ablation is highly effective in paroxysmal atrial fibrillation, pulmonary vein antral isolation (including posterior wall ...
Carola Gianni, Andrea Natale, Amin Al-Ahmad   +2 more
doaj   +4 more sources

Prospective Trial of Radiofrequency Catheter Ablation of High Dominant Frequencies After Pulmonary Vein Isolation in Non‐Paroxysmal Atrial Fibrillation (PAD‐AF Trial): A Multicenter, Randomized Clinical Trial

Journal of Cardiovascular Electrophysiology, EarlyView.
In persistent AF, adjunctive dominant frequency‐guided ablation after pulmonary vein isolation did not significantly improve outcomes. Limited overlap between high‐frequency sites and low‐voltage areas suggests functional–structural dissociation, while right atrial low‐voltage burden predicts recurrence.
Koji Kumagai, Tomoaki Hasegawa, Daisuke Kutsuzawa, Yuichi Hanaki, Masahide Harada, Hitoshi Hachiya, Yuhi Hasebe, Kazuki Noda, Minoru Yambe, Hirohito Metoki, Kazutaka Aonuma   +10 more
wiley   +1 more source

Clinical approach to paroxysmal atrial fibrillation [PDF]

Clinical Cardiology, 1990
AbstractIn addition to the role of the electrophysiological substrate, paroxysmal atrial fibrillation depends on the modulation of the atrial tissues by the autonomic nervous system. Experimentally, models of atrial fibrillation can be based on either adrenergic or vagal stimulations that provoke the arrhythmia by disturbing in a different way ...
openaire   +2 more sources

Prevalence and Recovery of Arrhythmia‐Induced Cardiomyopathy in Patients With Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real‐World Cohort Study

Journal of Cardiovascular Electrophysiology, EarlyView.
This graphical abstract summarizes the study design and main findings in patients with newly diagnosed left ventricular systolic dysfunction and concomitant arrhythmia undergoing early rhythm control under wearable cardioverter‐defibrillator protection.
Joerg Yogarajah, Jana Dannebaum, Ahmed Halim, Jamschid Sedighi, Matthias Mensch, Malte Kuniss, Thomas Neumann, Andreas Rieth, Julia Treiber, Samuel Sossalla, Andreas Hain   +10 more
wiley   +1 more source

Detection of Paroxysmal Atrial Fibrillation in Stroke/Tia Patients

Stroke Research and Treatment, 2013
One-third of stroke and transient ischemic attack (TIA) are cryptogenic, and paroxysmal atrial fibrillation (PAF) has been suggested as a possible cause for these cryptogenic strokes.
Muhib Khan, Daniel J. Miller
doaj   +1 more source

The effect of a case-finding app on the detection rate of atrial fibrillation compared with opportunistic screening in primary care patients: protocol for a cluster randomized trial

Trials, 2021
Background Atrial fibrillation is a cardiac arrhythmia commonly encountered in a primary care setting. Current screening is limited to pulse palpation and ECG confirmation when an irregular pulse is found.
Simon Gabriël Beerten, Tine Proesmans, Bert Vaes   +2 more
doaj   +1 more source