Results 141 to 150 of about 14,675 (263)

Paroxysmal motor signs in multiple sclerosis: an illustrative videotaped case. [PDF]

Oxf Med Case Reports
Lahmam G, Sikkal A, Khattab H, Haddouali K, Bellakhdar S, El Moutawakil B, Rafai MA, El Otmani H.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Severe Generalized Tetanus in a Chimpanzee (Pan troglodytes) Under Human Care: A Case Report from the Republic of Congo. [PDF]

Vet Sci
Fuertes-Recuero M, De Pablo-Moreno JA, Revuelta L, Cox D, Debenham J, Morón-Elorza P, De Pablo-Moreno JM, Atencia R.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Concomitant Intracardiac Shunt and Venous Collaterals After Fontan Procedure: A Case Report of Percutaneous Management. [PDF]

J Cardiovasc Dev Dis
Pintea Bentea G, Morissens M, Massart PE, Castro Rodriguez J.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Diagnostic Dilemma in an Infant With Sound-Triggered Motor Events: Reflex Epilepsy Versus Exaggerated Startle-A Case Report. [PDF]

Clin Case Rep
Pandit A, Koirala M, Shahi A, Sharma A, Panta A, Rimal S.   +5 more
europepmc   +1 more source

ATEBRIN IN PAROXYSMAL TACHYCARDIA AND PAROXYSMAL AURICULAR FIBRILLATION [PDF]

Heart, 1950
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Qualitative validation of TnED©, an electronic instrument capturing pain dimensions in patients with trigeminal neuralgia. [PDF]

J Oral Facial Pain Headache
Tahiri AS, Dodhia SA, Chotaliya S, Ansari H, Garibaldi G, Lasser R, Zakrzewska JM.   +6 more
europepmc   +1 more source