Results 221 to 230 of about 59,222 (317)

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Medicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang, Changling Xu, Jiangang Fan, Renjie Chai   +3 more
wiley   +1 more source

BINSEQ: A family of high-performance binary formats for nucleotide sequences. [PDF]

PLoS Comput Biol
Teyssier N, Dobin A.
europepmc   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

Med Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen, Chunrun Qu, Zeyu Wang, Jinglin Zhou, Hongwei Liu, Yingjie Li, Bowei Liu, Hao Zhang, Nan Zhang, Jingwei Zhang, Quan Cheng   +10 more
wiley   +1 more source

Distinct temporal dynamics of judging scene-relative object motion and estimating heading from optic flow. [PDF]

J Vis
Xie M, Li L.
europepmc   +1 more source

Omics GWAS: A Multi‐Omics Integrative Analysis Platform for Genome‐Wide Association Studies

Med Research, EarlyView.
ABSTRACT With the rapid advancement of genome‐wide association studies (GWAS), downstream analyses of GWAS data have become essential for elucidating the genetic mechanisms that underlie complex diseases. However, current post‐GWAS analyses face numerous challenges, including heterogeneous data formats, challenges in multi‐omics integration, and ...
Xu Zhang, Kailai Li, Yasi Zhang, Cenwen Liu, Shunyi Huang, Yingzhao Jin, Yugeng Gao, Quan Cheng, Yunyun Mei   +8 more
wiley   +1 more source

Latency-Aware Benchmarking of Large Language Models for Natural-Language Robot Navigation in ROS 2. [PDF]

Sensors (Basel)
Das M, Hussain Z, Nawaz M.
europepmc   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

Grammar error diagnosis using graph convolutional networks with knowledge graph integration. [PDF]

Sci Rep
Zhang J, Ma Y.
europepmc   +1 more source

DeepSeek‐Lattice‐KG: A Compact Language Model With Knowledge Graph Augmentation for Lattice Structure Design

Materials Genome Engineering Advances, EarlyView.
DeepSeek‐Lattice‐KG integrates a domain‐adapted 14B LLM with a Neo4j lattice knowledge graph distilled from 50,000 papers. It analyzes queries, retrieves supporting subgraphs, and generates grounded answers; on a 2100‐question, six‐domain benchmark, it achieves 94.8% accuracy.
Zhiyang Shu, Chao Wang, Changsheng Feng, Feiyu Zhou, Xueyan Chen, Yan Chen, Yilun Liu   +6 more
wiley   +1 more source

GazePlotter: An open-source solution for the automatic generation of scarf plots from eye-tracking data. [PDF]

Behav Res Methods
Vojtechovska M, Popelka S.
europepmc   +1 more source