Results 21 to 30 of about 362 (165)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Phantom citations: An empirical study of non‐existent and unverifiable references in scholarly literature

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The integrity of scholarly communication depends critically on the accuracy and verifiability of cited references. Citations enable readers to trace prior work, assess evidence, and situate new contributions within the existing literature. However, concerns have emerged regarding the presence of references in published papers that cannot be ...
Chengcheng Han, Sathiamoorthy Manoharan, Xinfeng Ye, Ulrich Speidel   +3 more
wiley   +1 more source

Utterance evolution: the road to generative, combinatorial communicators

Biological Reviews, EarlyView.
ABSTRACT Language has long been considered uniquely complex in the animal kingdom; however, animal research over the last decade has begun to challenge some long‐standing premises about exactly which language capacities are uniquely human. The task of resolving why and how complex communication systems evolve, particularly human language, has ...
Catherine Crockford, Roman Martin Wittig, Cedric Girard‐Buttoz   +2 more
wiley   +1 more source

Computational Model for Parsing Expression Grammars

CoRR
We present a computational model for Parsing Expression Grammars (PEGs). The predecessor of PEGs top-down parsing languages (TDPLs) were discovered by A. Birman and J. Ullman in the 1960-s, B. Ford showed in 2004 that both formalisms recognize the same class named Parsing Expression Languages (PELs). A. Birman and J.
Alexander A. Rubtsov, Nikita Chudinov
openaire   +4 more sources

A Graph‐Based Generative Artificial Intelligence Methodology for Autocorrection of Utility‐System P&IDs

Chemie Ingenieur Technik, EarlyView.
This work explores generative AI for automated revision of Piping and Instrumentation Diagrams (P&IDs). We frame P&ID correction as a translation problem, converting attributed P&ID graphs into sequences and learning revisions with a transformer‐based model.
Lukas Schulze Balhorn, Dominik P. Goldstein, Niels Seijsener, Kevin Dao, Ge H. M. Driessen, Artur M. Schweidtmann   +5 more
wiley   +1 more source

Exception Handling for Error Reporting in Parsing Expression Grammars [PDF]

, 2013
Parsing Expression Grammars (PEGs) are a new formalism to describe a top-down parser of a language. However, error handling techniques that are often applied to top-down parsers are not directly applicable to PEGs. This problem is usually solved in PEGs using a heuristic that helps to simulate the error reporting technique from top-down parsers, but ...
André Murbach Maidl, Fabio Mascarenhas, Roberto Ierusalimschy   +2 more
openaire   +1 more source

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

Reasoning BO: Enhancing Bayesian Optimization With the Reasoning Power of LLMs

Materials Genome Engineering Advances, EarlyView.
Addressing the challenge of too many parameters and too few experiments, reasoning BO enables AI‐accelerated scientific discovery. By searching smarter and reasoning deeper each round, this method achieves better results with fewer experiments than traditional approaches.
Zhuo Yang, Daolang Wang, Lingli Ge, Beilun Wang, Tianfan Fu, Yuqiang Li   +5 more
wiley   +1 more source

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Fragmentation Across Scales, Geography, and Climate Challenges in European Urban Climate Change Adaptation and Mitigation Research: A Bibliometric and Systematic Review

Sustainable Development, EarlyView.
ABSTRACT European urban climate change research lacks integration across scales, geography, and climate challenges, despite Europe's coordinated policy frameworks. Through a hybrid bibliometric and systematic review of 1528 studies (2010–2025) using Cortext Manager and PRISMA 2020 guidelines, this study maps the conceptual patterns, knowledge gaps, and
Isabela Pichardo‐Velázquez, Richard Dean Morales, Antonino Marvuglia   +2 more
wiley   +1 more source