Results 101 to 110 of about 3,582,018 (301)
, 2012 The simulation data presented here, and the conceptual framework developed for their interpretation are, both, in need of substantial refinement and extension.
Werner, prof. Gerhard
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Aristotle’s Hylomorphism: The Causal-Explanatory Model
Metaphysics, 2018 There are several innocuous or trivial ways in which to explicate Aristotle’s hylomorphism. For example: objects (or kinds of object) are characterisable in terms of matter and form; or analysable into matter and form; or understood on the basis of ...
Michail Peramatzis
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The 1900 Turn in Bertrand Russell’s Logic, the Emergence of his Paradox, and the Way Out [PDF]
, 2016 Russell’s initial project in philosophy (1898) was to make mathematics rigorous reducing it to logic. Before August 1900, however, Russell’s logic was nothing but mereology. First, his acquaintance with Peano’s ideas in August 1900 led him to discard the
Milkov, Nikolay
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
La partie et le tout sur le monde fragmentaire de Boris Pasternak
Revue des études slaves, 2016 This article offers a philosophical interpretation of Boris Pasternak’s work, based on the understanding of his strategy of writing, both poetic and prosaic, using the notion of fragment.
Ioulia Podoroga
doaj +1 more source
A Deep Cascade Network for Unaligned Face Attribute Classification
, 2017 Humans focus attention on different face regions when recognizing face attributes. Most existing face attribute classification methods use the whole image as input. Moreover, some of these methods rely on fiducial landmarks to provide defined face parts.
Chellappa, Rama +3 more
core +1 more source
Plant analysis as a tool to determine crop nitrogen status [PDF]
, 2007 An effective plant nutrient management strategy optimises nitrogen (N) use efficiency for minimised environmental impact, while ensuring an optimum N status of the crop for good product quality and maximum growth.
Ekbladh, Göran
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