Results 61 to 70 of about 16,290,303 (253)
Solusi Prediksi Persediaan Barang dengan Menggunakan Algoritma Apriori (Studi Kasus: Regional Part Depo Auto 2000 Palembang) [PDF]
, 2019 Dalam memprediksi persediaan barang banyak metode yang dapat dilakukan antara lain yaitu dengan melakukan pengolahan data penjualan menggunakan metode Data Mining yang disertai dengan algoritma apriori didasarkan pada proses pembelian yang dilakukan oleh
Ependi, Usman, Putra, Ade
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Successful treatment of generalized pustular psoriasis with guselkumab
Journal of Dermatological TreatmentThe purpose of the article: Generalized pustular psoriasis (GPP) is a rare auto-inflammatory disease. Patients with GPP may develop life-threatening complications, including sepsis, acute renal failure, neutrophilic cholangitis, high-output congestive ...
Martina Part
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Analysis of selected areas in inter-municipal cooperation
Medobčinsko sodelovanje predstavlja priložnost za oblikovanje politik, izvajanje ter zagotavljanje javnih služb, zastopanje interesov in izvajanje upravnih nalog. Savinjsko-šaleška regija ali s kratico SAŠA kljub manjšemu številu občin izstopa z razvitim
Part, Erika
core
Compositions of Being: Metaphysical and Non-Metaphysical Ways of Understanding and Discerning Them [PDF]
Studia Gilsoniana, 2017 This article discusses different ways of understanding compositions of being, and different methods for discerning them. It considers non-metaphysical (physical, scientistic, phenomenological, abstractionist) interpretations in order to decide whether ...
Andrzej Maryniarczyk
doaj