Multi-level physics informed deep learning for solving partial differential equations in computational structural mechanics. [PDF]
He W, Li J, Kong X, Deng L.
europepmc +1 more source
HYPERFUNCTIONS AND LINEAR PARTIAL DIFFERENTIAL EQUATIONS [PDF]
openaire +2 more sources
Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper +25 more
wiley +1 more source
Overcoming the curse of dimensionality in the numerical approximation of high-dimensional semilinear elliptic partial differential equations. [PDF]
Beck C, Gonon L, Jentzen A.
europepmc +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Bandgap Calculation and Experimental Analysis of Piezoelectric Phononic Crystals Based on Partial Differential Equations. [PDF]
Song C +5 more
europepmc +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Implicit Low-Rank Riemannian Schemes for the Time Integration of Stiff Partial Differential Equations. [PDF]
Sutti M, Vandereycken B.
europepmc +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Physics-informed genetic programming for discovery of partial differential equations from scarce and noisy data. [PDF]
Cohen BG, Beykal B, Bollas G.
europepmc +1 more source

