Results 41 to 50 of about 11,468 (258)

Orthogonalized Partial Directed Coherence for Functional Connectivity Analysis of Newborn EEG [PDF]

, 2012
The aim of this study is to develop a time-frequency method and test its applicability to investigating directional cortical connectivity in the newborn brain considering the effect of volume conduction. We modified time-varying partial directed coherence (tv-PDC) based on orthogonalization of the MVAR model coefficients to deal with the effect of ...
Omidvarnia A.H., Azemi G., Boashash B., O'Toole J.M., Colditz P., Vanhatalo S.   +5 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Canonical Information Flow Decomposition Among Neural Structure Subsets

Frontiers in Neuroinformatics, 2014
Partial directed coherence (PDC) and directed coherence (DC) which describe complementary aspects of the directed information flow between pairs of univariate components that belong to a vector of simultaneously observed time series have recently been ...
Daniel Yasumasa Takahashi, Luiz Antonio Baccala, Koichi eSameshima   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

High-dimensional multivariate autoregressive model estimation of human electrophysiological data using fMRI priors

NeuroImage, 2023
Multivariate autoregressive (MVAR) model estimation enables assessment of causal interactions in brain networks. However, accurately estimating MVAR models for high-dimensional electrophysiological recordings is challenging due to the extensive data ...
Alliot Nagle, Josh P. Gerrelts, Bryan M. Krause, Aaron D. Boes, Joel E. Bruss, Kirill V. Nourski, Matthew I. Banks, Barry Van Veen   +7 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Simulation Study of Direct Causality Measures in Multivariate Time Series

Entropy, 2013
Measures of the direction and strength of the interdependence among time series from multivariate systems are evaluated based on their statistical significance and discrimination ability.
Cees Diks, Catherine Kyrtsou, Dimitris Kugiumtzis, Angeliki Papana   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

RESILIENCE IN MIGRAINE BRAINS: DECREASE OF COHERENCE AFTER PHOTIC STIMULATION

Frontiers in Human Neuroscience, 2012
Background: During migraine attacks, patients generally have photophobia and phonophobia and seek for environments with less sensorial stimulation. Present work aimed to quantify cortical partial directed coherence (PDC) of electroencephalographic (EEG ...
Mayara eMendoca-de-Souza, Ubirakitan Maciel Monteiro, Amana Schweigert Bezerra, Ana Paula eSilva-de-Oliveira, Belvania Ramos Ventura-da-Silva, Marcelo Scarabel Barbosa, Josiane Alaide de Souza, Elisângela Cardoso Criado, Maria Carolina Martim Ferrarezi, Giselly de Andrade Alencar, Otavio Gomes Lins, Maria das Graças Wanderley de Sales Coriolano, Belmira Lara da Silveira Andrade da Costa, Marcelo Cairrão Araujo Rodrigues   +13 more
doaj   +1 more source

An Interpretable Machine Learning Method for the Detection of Schizophrenia Using EEG Signals

Frontiers in Systems Neuroscience, 2021
In this work we propose a machine learning (ML) method to aid in the diagnosis of schizophrenia using electroencephalograms (EEGs) as input data. The computational algorithm not only yields a proposal of diagnostic but, even more importantly, it provides
Manuel A. Vázquez, Arash Maghsoudi, Inés P. Mariño, Inés P. Mariño, Inés P. Mariño   +4 more
doaj   +1 more source