A Hypothesis for How Non‐REM Sleep Might Promote Seizures in Partial Epilepsies: A Transcranial Magnetic Stimulation Study [PDF]
, 2007 Farid Salih +5 more
openalex +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
Advanced Science, EarlyView.OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Genetic and Neuroanatomical Support for Functional Brain Network Dynamics in Epilepsy
, 2018 Focal epilepsy is a devastating neurological disorder that affects an overwhelming number of patients worldwide, many of whom prove resistant to medication.
Bassett, Danielle S. +8 more
core
Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes
Advanced Science, EarlyView.Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis +9 more
wiley +1 more source
Advanced Science, EarlyView.The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai +15 more
wiley +1 more source
Dominant partial epilepsies: A clinical, electrophysiological and genetic study of 19 European families [PDF]
, 2000 Fabienne Picard
openalex +1 more source
Advanced Science, EarlyView.A transfer‐free fabrication method enables multilayer graphene microelectrodes as small as 10 µm, eliminating reliability issues of manual graphene transfer. These electrodes record neural activity in brain slices with exceptional signal‐to‐noise ratios (up to 25–40 dB) while maintaining optical transparency for multimodal applications.
Nerea de Alvarez de Eulate +7 more
wiley +1 more source
Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat [PDF]
, 2007 Pierangelo Sardo, Giuseppe Ferraro
openalex +1 more source
Autosomal Dominant Partial Epilepsies
Pediatric Neurology Briefs, 2000 The clinical, electrophysiologic, and genetic characteristics of autosomal dominant partial epilepsy were studied in 71 patients and 33 non-epileptic at-risk family members in 19 European families followed at the Hopital Universitaire de Geneve, Switzerland, and centers in Strasbourg, Paris, Grenoble, Nice, Marseille, Rome, and Pisa.
openaire +3 more sources
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source