Results 161 to 170 of about 2,115,183 (392)

How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]

open access: yes, 2014
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano   +1 more
core   +1 more source

Memory and mood outcomes after anterior thalamic stimulation for refractory partial epilepsy

open access: yesSeizure, 2017
A. Tröster   +3 more
semanticscholar   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély   +5 more
wiley   +1 more source

Pregabalin in the management of partial epilepsy

open access: yesNeuropsychiatric Disease and Treatment, 2009
Amir M ArainVanderbilt University Medical Center, Department of Neurology, Nashville, TN, USAAbstract: Pregabalin is a new antiepileptic medication that works by binding to alpha 2 delta subunit of the voltage-dependent calcium channels present in ...
Amir M Arain
doaj  

Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders. [PDF]

open access: yes, 2019
BACKGROUND:Neurodevelopmental disorders (NDDs) such as autism spectrum disorder, intellectual disability, developmental disability, and epilepsy are characterized by abnormal brain development that may affect cognition, learning, behavior, and motor ...
Amini, Hajar   +7 more
core  

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy

open access: yesNeurology, 2015
V. Salanova   +27 more
semanticscholar   +1 more source

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