Results 241 to 250 of about 71,386 (306)

“The Most Difficult Conversations We Have”: Resident Experiences With Pediatric Neuroprognostication

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Pediatric neuroprognostication is often complicated by uncertainty and embedded in high‐stakes medical decisions. For child neurology residents, participation in neuroprognostication can represent key learning experiences but also comes with emotional and ethical challenges, which poses a risk of moral distress.
Grant L. Lin   +7 more
wiley   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba   +7 more
wiley   +1 more source

Efficacy of intravenous immunoglobulin in children with drug-resistant epilepsy. [PDF]

open access: yesFront Neurol
Ebdalla A   +4 more
europepmc   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study. [PDF]

open access: yesEpilepsia
Feng X   +11 more
europepmc   +1 more source

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