Results 51 to 60 of about 1,575,471 (293)

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Psychological distress among patients with epilepsy

open access: yesIndian Journal of Psychological Medicine, 2011
Background: Epilepsy is a disorder of the brain characterized by recurrent seizures which are physical reactions to sudden, usually brief, too much electrical discharges in a group of brain cells. Psychological distress often accompanies epilepsy.
Asma Khalid, Naeem Aslam
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Different Characteristics between the Generalized and Partial Epilepsy Based on the Family History of Epilepsy

open access: yesمجله دانشکده پزشکی اصفهان, 2016
Background: In etiology of epilepsy, different factors have role and one of them is genetics. This study aimed to investigate the differences between generalized and partial epilepsy based on the family history.
Mohammad Reza Najafi   +3 more
doaj  

Benign Partial Nonrolandic Epilepsies

open access: yesPediatric Neurology Briefs, 1991
The syndrome of benign partial epilepsy with particular reference to the non-rolandic types is described and the relevant literature reviewed from the Pediatric Seizure Clinic and EEG Laboratory, Beilinson Medical Center, Petah Tikva, and the Sackler ...
J Gordon Millichap
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Surgery for temporal lobe epilepsy in Semarang,Indonesia: The first 56 patients with follow up longer than 12 months [PDF]

open access: yes, 2006
Until October 2005, surgery were performed for 76 intractable temporal lobe epilepsy patients. Among them, 56 patients had follow-up of 12-76 months. The patients consisted of 35 males and 21 females,age between 3-38 year-old.
Muttaqin, Zainal
core   +2 more sources

EEG Maturational Changes in Partial Epilepsies

open access: yesPediatric Neurology Briefs, 1994
Changes and migration of EEG foci with age in 208 patients with childhood partial epilepsy followed for more than 3 years are reported from the Department of Pediatrics, Toyama Medical and Pharmaceutical University, Toyama City, Japan.
J Gordon Millichap
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Experiences in an Epilepsy Polyclinic: Epilepsy in the Elderly [PDF]

open access: yes, 2015
Objectives:Epilepsy is one of the most common serious neurological disorders in the elderly. In this study the demographic and clinical features, etiological factors, seizure types and response ratios to treatment are presented for a group of patients ...
Sevda Yıldız GÖKÇEER   +11 more
core   +1 more source

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