Results 51 to 60 of about 6,545,148 (269)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Massera type criterion for a partial neutral functional differential equation
Electronic Journal of Differential Equations, 2002 We prove the existence of periodic solutions for partial neutral functional differential equations with delay, using a Massera type criterion.
Eduardo Hernandez M.
doaj
Nonlinear functional integrodifferential equations in Hilbert space
International Journal of Mathematics and Mathematical Sciences, 1999 Let X be a Hilbert space and let Ω⊂Rn be a bounded domain with smooth boundary ∂Ω. We establish the existence and norm estimation of solutions for the parabolic partial functional integro-differential equation in X by using the fundamental solution.
J. Y. Park, S. Y. Lee, M. J. Lee
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Weak solutions of functional differential inequalities with first-order partial derivatives
Journal of Inequalities and Applications, 2011 The article deals with functional differential inequalities generated by the Cauchy problem for nonlinear first-order partial functional differential equations. The unknown function is the functional variable in equation and inequalities, and the partial
Kamont Zdzisław
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Implicit methods for the simple wave equation [PDF]
, 1984 A family of finite difference methods is developed for the numerical solution of the simple wave equation. Local truncation errors are cal- culated for each member of the family and each is analyzed for stability.
Tirmizi, S I A, Twizell, E H
core +5 more sources
S-asymptotically omega-periodic solutions for abstract neutral differential equations
Electronic Journal of Differential Equations, 2015 In this article we study the existence of S-asymptotically omega-periodic solutions for abstract neutral functional differential equations recently, introduced in the literature.
Michelle Pierri, Donal O'Regan
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source