Results 141 to 150 of about 367 (238)

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley   +2 more
wiley   +1 more source

Predicting the risk of cardiovascular disease in adults exposed to heavy metals: Interpretable machine learning

open access: yesEcotoxicology and Environmental Safety
Machine learning exhibits excellent performance in terms of predictive power. We aimed to construct an interpretable machine learning model utilizing National Health and Nutrition Examination Survey data to investigate the relationship between heavy ...
Meiyue Shen   +8 more
doaj  

Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im   +9 more
wiley   +1 more source

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

open access: yesAdvanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer   +8 more
wiley   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

open access: yesAdvanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen   +17 more
wiley   +1 more source

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba   +8 more
wiley   +1 more source

Morphogenic Growth 3D Printing

open access: yesAdvanced Materials, EarlyView.
I additive manufacturing process exploits the spatial propagation of a polymerization reaction front to produce 3D polymer parts 10× faster and 1000× more energy efficient than the fastest stereolithography. In contrast with existing 3D printing, this morphogenic process is inspired by biological “growth and form” due to the self‐directed propagation ...
Yun Seong Kim   +10 more
wiley   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

open access: yesAdvanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll   +16 more
wiley   +1 more source

High‐Yield Bioproduction of Extracellular Vesicles from Stem Cell Spheroids via Millifluidic Vortex Transport

open access: yesAdvanced Materials, EarlyView.
Stem cell spheroids, produced via a high‐throughput microfabrication technique, are transported within a vortex generated at the outlet channels of a cross‐slot millifluidic chip. For Reynolds number exceeding 170–200, intermittent high shear stresses applied to each spheroid within the vortex trigger a massive release of biologically active ...
Elliot Thouvenot   +8 more
wiley   +1 more source

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