Results 181 to 190 of about 176,958 (287)

Mechanistic deconvolution of BSA size variants by constrained Raman pseudo‐Voigt hard modeling during anion‐exchange chromatography

Biotechnology Progress, EarlyView.
Abstract In biopharmaceutical manufacturing, protein aggregation is a critical quality attribute, necessitating rapid and reliable analytical strategies during downstream processes like anion‐exchange chromatography (AEX). While Raman spectroscopy enables continuous monitoring of protein secondary structure, standard data‐driven regression models ...
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Prediction of gas chromatographic retention times of narcotic and hazardous drugs in blood using QSRR and machine learning models. [PDF]

RSC Adv
Shuheil MA, Aldulaimi A, Ray S, Qassem TA, Garg G, Sharma R, Urazbaeva D, Sadikova S, Safamanesh M.   +8 more
europepmc   +1 more source

Driving Fan Engagement: The Role of Orientation, Value Creation, and Community Dynamics in Sports Fan Pages

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Online fan communities are important peripheral arenas for sports consumption. However, the psychological and social mechanisms that sustain engagement across these digital spaces are not sufficiently understood. This study thus investigates how Orientation Toward Sporting Events (OSE) drives fan page engagement and, subsequently, satisfaction.
Hamid Shaker, Babak Taheri, Martin Gannon, Josip Mikulić   +3 more
wiley   +1 more source

Convolutional Neural Network-Based Models for Near-Infrared Prediction of Nutritional Quality in Multi-Product Animal Feeds. [PDF]

Animals (Basel)
Yang X, Liu Z, Yang F, Lin Y, Berzaghi P, Castillo-Girones S.   +5 more
europepmc   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

MATLAB-candexch algorithm-enhanced UV spectrophotometric-chemometric models for green, blue, and white determination of cinnarizine, domperidone, and carcinogenic impurity in pharmaceuticals: NQS assessment and UN-SDGs integration. [PDF]

BMC Chem
Ghanem HN, El-Zaher AA, Taha EA, Abbas AEF, Mahmoud ST.   +4 more
europepmc   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Sufficient and necessary conditions for ChatGPT adoption in medical education: a combined partial least square-structural equation modelling and necessary condition analysis. [PDF]

BMC Med Educ
Chew KS, Wong SS, Ooi SK, Lim ZJ, Jensen GG, Azri NNZK, Shanmuganathan L.   +6 more
europepmc   +1 more source

Do ESG‐Related Managerial Capabilities Pay Off for SMEs? Evidence From the Small and Medium‐Sized Enterprise ESG Capability Measure (SM‐ESG)

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Large companies have a long track record of environmental, social, and governance (ESG) initiatives, whereas many small and medium‐sized enterprises (SMEs) lag in adopting sustainability‐related practices, often acting voluntarily or in response to stakeholder pressures and incentives.
Vivien Csapi, Mónika Galambosné Tiszberger, Gábor Márkus, Ákos Tóth‐Pajor, Petra Putzer   +4 more
wiley   +1 more source

Candexch algorithm-enhanced chemometric determination of a novel anti-COVID-19 therapeutics in plasma and paxlovid formulation using advanced multivariate modeling: a sustainability-centered bioanalytical approach. [PDF]

BMC Chem
Abbas AEF, Talib NFA, Elghobashy MR, Al Kamaly O, Halim MK.   +4 more
europepmc   +1 more source