Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
The Impact of Exploitative Leadership and Moral Disengagement on Nurses' Work Withdrawal Behaviors: A Mediation Model Using the Partial Least Squares Approach. [PDF]
Abou Zeid MAG +2 more
europepmc +1 more source
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source
Simultaneous Quantitative Analysis of Polymorphic Impurities in Canagliflozin Tablets Utilizing Near-Infrared Spectroscopy and Partial Least Squares Regression. [PDF]
Liu M +6 more
europepmc +1 more source
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale +6 more
wiley +1 more source
The Utilization of Partial Least Squares for Simultaneous Feature Selection and Extraction
Several works concerning the utilization of Partial Least Squares as a supervised dimension reduction technique have been developed over the years in the field of chemometrics, among others, for regression purposes. However, Partial Least Squares can be
Elisavet Beki, Ntotsis Kimon
doaj
Chemical and Physicochemical Water Quality Parameters and Partial Least Squares Discriminant Analysis as Key Tools to Evaluate Dam Influence on Adjacent Surface Waters: Evidence from Bulgarian Reservoirs. [PDF]
Venelinov T +3 more
europepmc +1 more source
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
Karl Popper and the Mechanisms of Hydrogen Embrittlement
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley +1 more source
Beyond linearity - a new Partial Least Squares - Path Modelling (PLS-PM) inner weighting scheme for detecting and approximating nonlinear structural relationships in Structural Equation Models. [PDF]
Mendes JM, Coelho PS.
europepmc +1 more source

