Results 61 to 70 of about 880,930 (320)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Key issues on partial least squares (PLS) in operations management research: A guide to submissions [PDF]

open access: yes, 2019
Purpose: This work aims to systematise the use of PLS as an analysis tool via a usage guide or recommendation for researchers to help them eliminate errors when using this tool.
Alfalla Luque, Rafaela   +1 more
core   +4 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The Use of Partial Least Squares Method To Remove Multicollinearity [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2010
In this research the estimation of the regression parameters was clarified using least squares and partial least squares compared with the normal method in terms of its ability to be free from the problem of Multicollinearity between the predictive ...
doaj   +1 more source

Non-Metric Partial Least Squares

open access: yesElectronic Journal of Statistics, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A Partial Least Squares based algorithm for parsimonious variable selection

open access: yesAlgorithms for Molecular Biology, 2011
Background In genomics, a commonly encountered problem is to extract a subset of variables out of a large set of explanatory variables associated with one or several quantitative or qualitative response variables.
Mehmood Tahir   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Downscaling GRACE total water storage change using partial least squares regression

open access: yesScientific Data, 2021
Measurement(s) Gravity Technology Type(s) gravity field theory • computational modeling technique Factor Type(s) geographic location • temporal interval Sample Characteristic - Environment water body Sample Characteristic - Location global Machine ...
Bramha Dutt Vishwakarma   +2 more
doaj   +1 more source

Partial least squares for face hashing [PDF]

open access: yesNeurocomputing, 2016
Face identification is an important research topic due to areas such as its application to surveillance, forensics and human-computer interaction. In the past few years, a myriad of methods for face identification has been proposed in the literature, with just a few among them focusing on scalability.
dos Santos, Cassio   +3 more
openaire   +1 more source

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