Results 91 to 100 of about 2,429,367 (395)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Melt extraction from partially molten peridotites

open access: yesGeochemistry, Geophysics, Geosystems, 2003
We measured the rate of melt extraction from partially molten olivine aggregates into a porous reservoir as a function of melt content (ϕ), melt viscosity, grain size, and pressure difference. Samples were prepared using mixtures of olivine and either lithium silicate, MORB glass, or albite glass to obtain a range in melt viscosities.
Jörg Renner   +3 more
openaire   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Theory of Decoupling in the Mixed Phase of Extremely Type-II Layered Superconductors

open access: yes, 2001
The mixed phase of extremely type-II layered superconductors in perpendicular magnetic field is studied theoretically via the layered XY model with uniform frustration. A partial duality analysis is carried out in the weak-coupling limit. It consistently
A. E. Koshelev   +65 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

What controls partial melting in migmatites? [PDF]

open access: yesJournal of Metamorphic Geology, 1988
Abstract The layers of six stromatic migmatites from Northern, Western, and Central Europe display small but systematic chemical and mineralogical differences. At least five of these migmatites do not show any signs of largescale metamorphic differentiation, metasomatism, or segregation of melts. It is concluded, therefore, that the compositional
openaire   +1 more source

Carboniferous and Permian magmatism in Scotland [PDF]

open access: yes, 2004
Extensional tectonics to the north of the Variscan Front during the Early Carboniferous generated fault-controlled basins across the British Isles, with accompanying basaltic magmatism.
Fitton, J.G.   +4 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

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