Results 41 to 50 of about 1,115,339 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Multiple fixed point theorems for contractive and Meir-Keeler type mappings defined on partially ordered spaces with a distance

open access: yesApplied General Topology, 2017
We introduce and study a general concept of multiple fixed point for mappings defined on partially ordered distance spaces in the presence of a contraction type condition and appropriate monotonicity properties.
Mitrofan M Choban, Vasile Berinde
doaj   +1 more source

Lazy buffer semantics for partial order scenarios

open access: yes, 2007
There exists a unique minimal generalisation of a UML sequence diagram (SD) that is race free, known as the inherent causal scenario. However, practitioners sometimes regard this solution as invalid since it is a purely mathematical construct that ...
Mitchell, Bill, Bill Mitchell
core   +1 more source

Lexicographic Partial Order [PDF]

open access: yesTransactions of the American Mathematical Society, 1978
Given a (partially) ordered set P with the descending chain condition, and an ordered set Q , the set
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Morphisms and Order Ideals of Toric Posets

open access: yesMathematics, 2016
Toric posets are in some sense a natural “cyclic” version of finite posets in that they capture the fundamental features of a partial order but without the notion of minimal or maximal elements.
Matthew Macauley
doaj   +1 more source

Partial Order Rank Features in Colour Space

open access: yesApplied Sciences, 2020
Partial orders are the natural mathematical structure for comparing multivariate data that, like colours, lack a natural order. We introduce a novel, general approach to defining rank features in colour spaces based on partial orders, and show that it is
Fabrizio Smeraldi   +3 more
doaj   +1 more source

Noise Removal Based on Fourth Order Partial Differential Equation

open access: yes, 2008
Noise removal is an important image processing problem which has wide applications in different fields. The noise removal and edge preservation algorithm based on variational method and partial differential equation (PDE) for processing Magnetic ...
Zhifeng Wang   +5 more
core   +1 more source

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