Results 121 to 130 of about 1,017,520 (318)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Design and Control of Fractional-Order Systems Based on Fractal Operators

Fractal and Fractional
In recent years, we have abstracted physical fractal space from biological structures and movements within living organisms, revealing the profound intrinsic connections between fractional order time and fractional-dimensional space, and providing ...
Zhimo Jian, Chaoqian Luo, Yajun Yin
doaj   +1 more source

Novel Dynamic Partial Reconfiguration Implementation of K-Means Clustering on FPGAs: Comparative Results with GPPs and GPUs

International Journal of Reconfigurable Computing, 2012
K-means clustering has been widely used in processing large datasets in many fields of studies. Advancement in many data collection techniques has been generating enormous amounts of data, leaving scientists with the challenging task of processing them ...
Hanaa M. Hussain, Khaled Benkrid, Ali Ebrahim, Ahmet T. Erdogan, Huseyin Seker   +4 more
doaj   +1 more source

An efficient construction of polar codes based on the general partial order

EURASIP Journal on Wireless Communications and Networking, 2019
Traditionally, the construction of polar codes requires intense computations to sort all bit channels. In previous works, two types of partial orders (POs) of polar codes were proposed to decrease the computations in the construction process.
Wei Wang, Liping Li, Kai Niu
doaj   +1 more source

Preferences over Meyer’s Location-Scale Family [PDF]

This paper extends Meyer’s (1987) location-scale family with general n random seed sources. Firstly, we clarify and generalize existing results to this multivariate setting.
Chenghu Ma, Wing-Keung Wong
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Dead Ends in Misere Play: The Misere Monoid of Canonical Numbers

, 2013
We find the misere monoids of normal-play canonical-form integer and non-integer numbers. These come as consequences of more general results for the universe of `dead-ending' games.
Milley, Rebecca, Renault, Gabriel
core   +1 more source

Generalized second-order partial derivatives of 1/ r [PDF]

European Journal of Physics, 2011
12 pages; as accepted for publication by European Journal of ...
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Push-pull alkenes: structure and p-electron distribution [PDF]

Journal of the Serbian Chemical Society, 2006
Push-pull alkenes are substituted alkenes with one or two electron-donating substituents on one end of C=C double bond and with one or two electron-accepting substituents at the other end.
ERICH KLEINPETER
doaj