Results 51 to 60 of about 1,488,319 (298)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

On the regularity and partial regularity of extremal solutions of a Lane–Emden system [PDF]

Proceedings of the American Mathematical Society, 2019
In this paper, we consider the system − Δ
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Partial compactness for the 2-D Landau-Lifshitz flow

Electronic Journal of Differential Equations, 2004
Uniform local $C^infty$-bounds for Ginzburg-Landau type approximations for the Landau-Lifshitz flow on planar domains are proven. They hold outside an energy-concentration set of locally finite parabolic Hausdorff-dimension 2, which has finite ...
Paul Harpes
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Estimates for evolutionary partial differential equations in classical function spaces

Forum of Mathematics, Sigma, 2023
We establish new local and global estimates for evolutionary partial differential equations in classical Banach and quasi-Banach spaces that appear most frequently in the theory of partial differential equations.
Alejandro J. Castro, Anders Israelsson, Wolfgang Staubach, Madi Yerlanov   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Pattern avoidance in partial permutations [PDF]

, 2011
Motivated by the concept of partial words, we introduce an analogous concept of partial permutations. A partial permutation of length n with k holes is a sequence of symbols $\pi = \pi_1\pi_2 ...
Claesson, A., Jelinkova, E., Jelinek, V., Kitaev, S.   +3 more
core   +3 more sources

Existence and regularity theorems for d and ∂̄ $\bar{\partial }$ in Hölder–Zygmund spaces on half-spaces

Demonstratio Mathematica
This paper is devoted to establish existence and regularity theorems for the d- and ∂̄ $\bar{\partial }$ -equations in the domains C+n ${\mathbb{C}}_{+}^{n}$ and R+n+1 ${\mathbb{R}}_{+}^{n+1}$ , respectively, for differential forms in Hölder–Zygmund ...
Khidr Shaban, Sambou Salomon
doaj   +1 more source

Regularity Result for Quasilinear Elliptic Systems with Super Quadratic Natural Growth Condition

Abstract and Applied Analysis, 2013
We consider boundary regularity for weak solutions of second-order quasilinear elliptic systems under natural growth condition with super quadratic growth and obtain a general criterion for a weak solution to be regular in the neighborhood of a given ...
Shuhong Chen, Zhong Tan
doaj   +1 more source