Results 91 to 100 of about 163,376 (352)
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Drug Design, Development and Therapy, 2017 Michele A Faulkner1,2 1Department of Pharmacy Practice, 2Department of Neurology, Creighton University Schools of Pharmacy and Medicine, Omaha, NE, USA Purpose: Perampanel is a first-in-class antiepileptic medication approved for the treatment of partial
Faulkner MA
doaj
Musicogenic Epilepsy in An Infant
Pediatric Neurology Briefs, 2003 A 6-month-old infant with seizures triggered by loud music, especially specific songs of the Beatles, is reported from Chang Gung Children’s Hospital at Linkou, Taoyuan, Taiwan.
J Gordon Millichap
doaj +1 more source
Neuro radio logic diagnostic evaluation of partial seizure in children’s
, 2023 Tejanjani Vathada, Rajashekar Alishala
openalex +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Treatment options for refractory and difficult to treat seizures: focus on vigabatrin
Therapeutics and Clinical Risk Management, 2011 Justin A Tolman, Michele A FaulknerSchool of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska, NE, USAAbstract: Complex partial seizures are often refractory to current pharmacological therapies.
Tolman JA, Faulkner MA
doaj
Brain Mechanisms of Altered Consciousness in Focal Seizures
Behavioural Neurology, 2011 Consciousness is a central concept in epileptology, relevant to the understanding of both focal and generalized seizures. Within focal seizures, impairment of consciousness has long been considered as the main criterion differentiating complex partial ...
Andrew P. Bagshaw, Andrea E. Cavanna
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source