Results 281 to 290 of about 163,376 (352)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Prevalence, characteristics, and treatment outcomes of epilepsy in Nigeria: a systematic review and meta-analysis. [PDF]

Eur J Med Res
Aderinto N, Ukoaka B, Olatunji G, Kokori E, Afolabi S, Babalola AE, Yusuf I, Ogieuhi IJ, Moradeyo A, Obasanjo OM, Oluwakorede A, Omoworare O, Adebayo YA.   +12 more
europepmc   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Identification of Additional Cases of Severe Neonatal GABA-Transaminase Deficiency. [PDF]

JIMD Rep
Alammary D, Low T, Srinivasan G, Dery MC, Almutadares M, Marin S, Rafay MF, Rozovsky K, Frosk P.   +8 more
europepmc   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Prognosis of people with focal epilepsy treated with anti-seizure medications (ASMs): a narrative review of current evidence and future directions. [PDF]

BMJ Neurol Open
Barnard S, Foster E, Kwan P, French JA, O'Brien TJ.   +4 more
europepmc   +1 more source

<i>LAMA2</i> variants associated with muscular dystrophy, brain structural abnormalities, and epilepsy: a genotype-phenotype study. [PDF]

Front Neurol
Zha J, Yu Y, Cao F, Yi Z, Wu H, Chen Y, Zhong J, Yu X.   +7 more
europepmc   +1 more source

Lidocaine as a potential anti-seizure therapy for pediatric FIRES: a promising therapeutic approach. [PDF]

Front Pediatr
Yang Y, Wei N, Guan Q, Xie H, Huang X, Ru X, Wu Y, Wang Y, Sang T.   +8 more
europepmc   +1 more source

Dyke-Davidoff-Masson Syndrome in Pediatrics: Case Report of Atypical Status Epilepticus and Therapeutic Challenges in the Caribbean. [PDF]

Case Rep Med
Martín-Sanz MB, Lucas-Muñoz D, Colomé-Hidalgo M, Vásquez-Gómez G.   +3 more
europepmc   +1 more source