Results 71 to 80 of about 163,376 (352)
Ictal kissing: occurrence and etiology. [PDF]
, 2016 Ictal kissing is a rare semiological manifestation in patients with epilepsy. We tried to estimate its occurrence and characterize the underlying etiology.
Asadi-Pooya, Ali Akbar +1 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Topiramate Adjunctive Therapy for Partial Seizures
Pediatric Neurology Briefs, 1999 The efficacy and safety of topiramate (TPM) (6 mg/kg/day) in children age 2 to 16 years, as adjunctive therapy for uncontrolled partial-onset seizures (75% complex partial), with or without secondarily generalized seizures, were evaluated in a ...
J Gordon Millichap
doaj +1 more source
The long-term prognosis of epilepsy patients with medically treated over a period of eight years in Turkey. [PDF]
, 2017 OBJECTIVE:The aim of this study was to investigate the effect of demographic and clinical characteristics on temporal changes in seizure control and frequency in medically treated epilepsy patients to guide treatment modalities.
Duman, Pelin +2 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Gabapentin Add-On Therapy for Partial Seizures
Pediatric Neurology Briefs, 2001 The efficacy and safety of gabapentin (GBP) as add-on therapy in 237 children, aged 3 to 12 years, with refractory partial seizures were studied at the Alder Hey Children’s Hospital, Liverpool, UK.
J Gordon Millichap
doaj +1 more source
Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]
, 2016 Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe +20 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Prognosis of Neonatal Seizures
Pediatric Neurology Briefs, 1991 The neurologic outcome of 40 infants with EEG documented seizures of diverse etiologies was examined retrospectively at the Division of Neurology, The Children’s Hospital of Philadelphia, PA.
J Gordon Millichap
doaj +1 more source
EEG–fMRI of idiopathic and secondarily generalized epilepsies [PDF]
, 2006 We used simultaneous EEG and functional MRI (EEG–fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE).
Duncan, J.S. +7 more
core +1 more source