Results 61 to 70 of about 95,601 (295)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Multi-word expression-sensitive word alignment [PDF]
, 2010 This paper presents a new word alignment method which incorporates knowledge about Bilingual Multi-Word Expressions (BMWEs). Our method of word alignment first extracts such BMWEs in a bidirectional way for a given corpus and then starts conventional ...
Maldonado Guerra, Alfredo +3 more
core
Partial word order freezing in Dutch
, 2012 Dutch allows for variation as to whether the first position in the sentence is occupied by the subject or by some other constituent, such as the direct object.
Bouma, G.J., Hendriks, P.; id_orcid
core +2 more sources
A NOTE ON THE NUMBER OF SQUARES IN A PARTIAL WORD WITH ONE HOLE [PDF]
, 2009 A well known result of Fraenkel and Simpson states that the number of distinct squares in a word of length n is bounded by 2n since at each position there are at most two distinct squares whose last occurrence starts.
Blanchet-Sadri, Francine +1 more
core +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Periods, partial words, and an extension of a result of Guibas and Odlyzko [PDF]
, 2007 "A well known and unexpected result of Guibas and Odlyzko states that the set of all periods of a word is independent of the alphabet size (alphabets with one symbol are excluded here).
Shirey, Brian +1 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Partial Sums on the Ultra-Wide Word RAM
, 2020 We consider the classic partial sums problem on the ultra-wide word RAM model of computation. This model extends the classic w-bit word RAM model with special ultrawords of length bits that support standard arithmetic and boolean operation and scattered ...
Bille, Philip +5 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source