Results 151 to 160 of about 937,585 (275)
Abstract The treatment scenario for newly‐diagnosed transplant‐ineligible multiple myeloma patients (NEMM) is quickly evolving. Currently, combinations of proteasome inhibitors and/or immunomodulatory drugs +/− the monoclonal antibody Daratumumab are used for first‐line treatment, even if head‐to‐head comparisons are lacking.
Cirino Botta+17 more
wiley +1 more source
Model Bias Identification for Bayesian Calibration of Stochastic Digital Twins of Bridges
ABSTRACT Simulation‐based digital twins must provide accurate, robust, and reliable digital representations of their physical counterparts. Therefore, quantifying the uncertainty in their predictions plays a key role in making better‐informed decisions that impact the actual system.
Daniel Andrés Arcones+3 more
wiley +1 more source
Abstract The standardization of variant curation criteria is essential for accurate interpretation of genetic results and clinical care of patients. The variant curation guidelines developed by the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) in 2015 are widely used but are not gene specific.
Kathryn P. Burdon+14 more
wiley +1 more source
Comparing Risks for Binomial Reliability Assurance Test Planning
ABSTRACT Balancing consumer's and producer's risk is an important consideration when planning tests. Instead of focusing on finding a single best test plan, we introduce a general framework to systematically identify a set of binomial test plans by leveraging the inverse relationship between the two risks.
Hyoshin Kim, Alyson G. Wilson
wiley +1 more source
Abstract Developing population models for assessing risks to terrestrial plant species listed as threatened or endangered under the Endangered Species Act (ESA) is challenging given a paucity of data on their life histories. The purpose of this study was to develop a novel approach for identifying relatively data‐rich nonlisted species that could serve
Pamela Rueda‐Cediel+5 more
wiley +1 more source
Anderson Acceleration for Partially Observable Markov Decision Processes: A Maximum Entropy Approach
Mingyu Park, Jae-Uk Shin, Insoon Yang
openalex +2 more sources
Making colonoscopy‐based screening more efficient: A “gateopener” approach
What's new? Although colonoscopy is a widely used screening tool for colorectal cancer (CRC), it is relatively inefficient, as most of the screened subjects would never develop CRC even without screening. In the present study, use of a low‐threshold fecal immunochemical test (“gateopener” FIT) was investigated as a means of streamlining screening ...
Thomas Heisser+4 more
wiley +1 more source
Understand funding liquidity and market liquidity in a regime‐switching model
Abstract We investigate the time‐varying relationship of funding liquidity (FL) and market liquidity (ML) in a Markov regime‐switching model. By using a comprehensive U.S. TRACE dataset, we provide strong evidence that FL and corporate bond ML are interlinked, and their impact on each other is highly regime‐dependent.
Louisa Chen, Liya Shen, Zhiping Zhou
wiley +1 more source