Results 61 to 70 of about 35,395 (320)
Advanced Science, EarlyView.Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen +10 more
wiley +1 more source
Optimal sequential decision making with probabilistic digital twins
SN Applied Sciences, 2023 In this study, we present a formal definition of the probabilistic digital twin (PDT). Digital twins are emerging in many industries, typically consisting of simulation models and data associated with a specific physical system.
Christian Agrell +2 more
doaj +1 more source
A tractable DDN-POMDP Approach to Affective Dialogue Modeling for General Probabilistic Frame-based Dialogue Systems [PDF]
, 2006 We propose a new approach to developing a tractable affective dialogue model for general probabilistic frame-based dialogue systems. The dialogue model, based on the Partially Observable Markov Decision Process (POMDP) and the Dynamic Decision Network ...
Bui, Trung H. +3 more
core +3 more sources
Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota
Advanced Science, EarlyView.This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo +11 more
wiley +1 more source
Advanced Science, EarlyView.HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li +8 more
wiley +1 more source
Toward Affective Dialogue Modeling using Partially Observable Markov Decision Processes [PDF]
, 2006 We propose a novel approach to developing a dialogue model which is able to take into account some aspects of the user’s emotional state and acts appropriately.
Bui, T.H. +3 more
core +1 more source
Advanced Science, EarlyView.scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley +1 more source
Improving Automated Driving through Planning with Human Internal States
, 2020 This work examines the hypothesis that partially observable Markov decision process (POMDP) planning with human driver internal states can significantly improve both safety and efficiency in autonomous freeway driving.
Kochenderfer, Mykel, Sunberg, Zachary
core
Monte Carlo Bayesian Reinforcement Learning [PDF]
, 2012 Bayesian reinforcement learning (BRL) encodes prior knowledge of the world in a model and represents uncertainty in model parameters by maintaining a probability distribution over them.
Hsu, David +3 more
core +1 more source
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Advanced Science, EarlyView.Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source