Results 141 to 150 of about 6,955,994 (297)
A Tutte Polynomial for Partially Ordered Sets
We investigate the Tutte polynomial of a greedoid associated to a partially ordered set. In this case, we explore the deletion-contraction formula in two ways and develop an antichain expansion for the polynomial. We show that the polynomial can determine the number of order ideals, order filters and antichains of all sizes of a poset \(P\), but ...
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Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Metrics on partially ordered sets—A survey
AbstractWe review more or less recent results on metrics associated with valuations or (and) minimum weighted paths in posets, metric characterizations of posets and we point out some applications of these results to problems involving uses of distances in social sciences.
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This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Extensions of Partially Ordered Sets [PDF]
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Partially Ordered Sets Associated with Permutations
Let \(\Sigma\) be a set of permutations of \([n]=\{1,...,n\}\). A poset P is called chain-permutational with respect to \(\Sigma\) iff the edges of the Hasse diagram of P can be labeled with labels from [n] so that the sequence of labels along each maximal chain of P is a permutation in \(\Sigma\), each permutation in \(\Sigma\) arises exactly once in ...
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The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
On Lattice Embeddings for Partially Ordered Sets
Let P be a set partially ordered by a (reflexive, antisymmetric, and transitive) binary relation ≺. Let be the family of all subsets K of P having the property that x ∈ P and y ∈ K and y ≺ x imply x ∈ K.
Truman Botts
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source

