Results 111 to 120 of about 514,221 (275)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
ATTITUDES TOWARDS JAVANESE LANGUAGE AND ITS MAINTENANCE BY THE ENGLISH DEPARTMENT STUDENTS OF DIPONEGORO UNIVERSITY [PDF]
, 2015 English Department Students of Undip whose parents are Javanese have been exposed to at least three languages namely Javanese, Indonesian, and English. Some of them are learning other foreign languages such as Korean, Japanese, and French.
Nirmala, Deli
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Ethnography From the Inside: Industry-based Research in the Commercial Sydney EDM Scene
Dancecult: Journal of Electronic Dance Music Culture, 2013 Drawing on a decade of ethnographic research and participant observation in the Sydney commercial electronic dance music (EDM) scene, this article explores some of the issues and tensions in conducting industry-based fieldwork in EDM culture.
Ed Montano
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Forum: Qualitative Social Research, 2000 This contribution describes the problems and pitfalls associated with the use of (participant) observation in nursing home wards for people suffering from dementia.
Anja Declercq
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Sport Karate and the Pursuit of Wellness: A Participant Observation Study of a dojo in Scotland. [PDF]
Front Sociol, 2020 Turelli FC +3 more
europepmc +1 more source
Dying for it: gangs, violence, and social change in urban Nicaragua [PDF]
, 2003 Youth gangs potentially constitute an ideal lens through which to explore the dynamics and ramifications of the new political economy of violence in Latin America, and this paper consequently presents and ethnographic case study of an urban Nicaraguan ...
Rodgers, Dennis
core