Results 131 to 140 of about 514,221 (275)

Ethical Challenges in Participant Observation: A Reflection on Ethnographic Fieldwork [PDF]

open access: yes, 2008
In this essay I reflect on the ethical challenges of ethnographic fieldwork I personally experienced in a female gambling study. By assuming a covert research role, I was able to observe natural occurrences of female gambling activities but unable to ...
Li, Jun
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Dramaturgies of participation. La Trilogia della guerra: Collaborating in the Staging of the Tragic

open access: yespiano b
This article aims to explore how theatre can fully express its potential within a participatory and political framework, presenting the initial findings of an ethnographic study focused on the main ways in which a theatrical performance can create an ...
Federico Boni
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Using ethnographic methods to explore masculinities at school: reflections on participant observation with young men in New Delhi, India [PDF]

open access: yes, 2014
This paper outlines findings on masculinities and violence from my multi-method PhD study, which explored young people's experiences of learning about gender and sexuality in three co-educational, English-medium secondary schools in New Delhi, India.
Iyer, Padmini
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The “new managerialism”: Experiences of introducing formal management education into the public sector through the mechanism of the MBA dissertation [PDF]

open access: yes, 2007
Paper presented at the 3rd international Integrating for Excellence conference at Sheffield Hallam University in Sheffield, UK, 27-28 June 2007.This paper reflects upon the authors' experience of supervising dissertations on a public sector executive MBA
Page, Steve, Proctor, Tony, Webb, Paul
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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