Results 211 to 220 of about 1,686,472 (316)

Participant lived experiences of high-intensity interval training in UK cardiac rehabilitation (HIIT or MISS UK): A qualitative study. [PDF]

PLoS One
Williams C, Neil R, Powell R, Begg B, Birkett S, Nichols S, Ennis S, Banerjee P, Ingle L, Shave R, McGregor G.   +10 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Patient Experiences With GLP-1 Receptor Agonists.

JAMA Netw Open
de Vere Hunt I, Ramirez-Posada M, Babu CS, Brown-Johnson C, Linos E, Rodriguez F.   +5 more
europepmc   +1 more source

The Positive and Negative Impacts of Researching Emotionally Challenging Topics. [PDF]

J Acad Ethics
Brance K, Skinner TN, Halligan SL, Girling H, Tsang E.   +4 more
europepmc   +1 more source

Participation and responsibility [PDF]

Anais Brasileiros de Dermatologia, 2019
openaire   +4 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Delivering Health Coaching in a Student-Led Telehealth Clinic: Evaluating the Impact on Health-Related Quality of Life. [PDF]

Int J Telemed Appl
Matthews K, Haines T.
europepmc   +1 more source

Participant Index

Innovation in Aging, 2022
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

"Truly having a conversation with each member about their needs": accessibility considerations for the engagement of people with lived and living experience and caregivers in mental health and substance use health research. [PDF]

Res Involv Engagem
Hawke LD, Dada-Phillips W, Munro C, Hauer S, Sendanyoye C, Upham K, Kesteren MRV, Amartey A, Lunsky Y, Halsall T.   +9 more
europepmc   +1 more source