Results 81 to 90 of about 3,223,143 (258)

Advance directives as a care planning tool for patients with complex mental health needs: service evaluation

BJPsych Bulletin
Aims and method This study investigated the prevalence of advance directives among patients receiving community care within the East London NHS Foundation Trust (ELFT), and to identify factors associated with their clinical application.
Immanuel Amrita Rhema, Mohamed Ibrahim, Hajara Begum, Paul Binfield, Doris McMeel, Sophia Parveen, Lara O’Connell, Frank Röhricht   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Wako Cohort Study: Design and Profile of Participants at Baseline

Journal of Epidemiology
Background: We launched the Wako Cohort Study in 2023 to identify individual and socio-environmental factors related to the extension of healthy life expectancy and the reduction of health disparities among community-dwelling adults and to develop health
Yuri Yokoyama, Yu Nofuji, Takumi Abe, Kumiko Nonaka, Yumi Ozone, Yuka Nakamura, Shiina Chiaki, Takumi Suda, Naoko Saito, Mai Takase, Hidenori Amano, Susumu Ogawa, Hiroyuki Suzuki, Hiroshi Murayama   +13 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Impact of the First–Fourth Waves of the COVID-19 Pandemic on New Applications for Long-term Care Insurance in a Metropolitan Area of Japan

Journal of Epidemiology, 2022
Satoshi Seino, Shoji Shinkai, Akihiko Kitamura, Yu Nofuji, Yuri Yokoyama, Toshiki Hata, Yoshinori Fujiwara   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

EMPLOYEE PARTICIPATION IN EUROPE [PDF]

The goal of this study was to identify the determinants of employee participation in organizations across Europe. Power distance, uncertainty avoidance, competition, unionisation, sector, organizational size and business strategy were all expected to ...
Ángel Cabrera, Elizabeth F. Cabrera, Jaime Ortega   +2 more
core  

Psychosocial barriers to participation in adult learning and education: Applying a PsychoSocial Interaction Model

, 2018
Magister Educationis (Adult Learning and Global Change) - MEd(AL)Adult learners’ perception of factors that are internal to their perceived control of their lives can be challenging to overcome when making a decision to participate in learning.
Adams-Gardner, Myrtle
core   +1 more source

The Jigsaw teaching method compared to traditional teaching on anatomy and physiology knowledge in higher education – a randomised controlled trial

BMC Medical Education
Background Traditional teaching (TT) is lecturer-centred, while student-centred teaching, including Jigsaw (JS), fosters student interaction. However, the results of research on the effectiveness of JS on learning outcomes is inconsistent.
Janette Moland Stokstad, Eirik Solberg Nedrehagen, Karl Ove Hufthammer   +2 more
doaj   +1 more source