Results 51 to 60 of about 1,037,380 (308)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Determination of Performance Ranking of Participation Banks with CIRITIC-Based TOPSIS Method
Sakarya Üniversitesi İşletme Enstitüsü Dergisi: Participation banks are an essential part of the financial sector and have a unique business model that differs from traditional banks. These banks operate based on Islamic finance principles and strive to provide interest-free and ethical financial ...
Ömer Faruk Rençber +1 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
IMF Bank-Restructuring Efficiency Outcomes: Evidence from East Asia [PDF]
We report new findings on bank efficiency in East Asian countries for the preand post-IMF restructuring periods. We find that bank efficiency has improved, but only to the pre-IMF intervention level, and that restructured banks are not more efficient ...
Luc Can, Mohamed Ariff
core +3 more sources
Katılım Bankacılığı Hizmet İhtiyaç Finansmanının Fıkhi Açıdan Değerlendirilmesi
Kocatepe İslami İlimler Dergisiİnsanlar tarih borunca ihtiyaçlarını gidermek için gerekli olan parayı bulmak adına borç ilişkisi içerisine girmişlerdir. Zamanla insanların borç ihtiyaçlarını giderecek bankalar kurulmaya başlanmıştır. Ancak bankaların sermaye ihtiyaçlarını faizli kredi
Cemil Liv
doaj +1 more source
Communication and performance in Bank–Fund joint participation [PDF]
Research in Economics, 2015 Abstract In this paper I relate Bank–Fund performance to their willingness (or ability) to communicate. I find evidence that a Bank–Fund simultaneous loan is associated to an increase in economic growth and that such effect is diminished by factors preventing full communication, such as the degree of Bank-Fund competition and the salience of ...
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Islamic EconomicsTürkiye’de ilk olarak 1980’li yıllarda bankacılık sisteminin içerisinde yer alan İslami finans anlayışı, bugün itibariyle tüm bankacılık sistemi içerisinde yüzde 9’a yakın pazar payı ve üzerine çok sayıda akademik çalışma yapılan bir alan haline ...
Ünal Efe, Ahmet Çakmak
doaj +1 more source