Results 221 to 230 of about 519,125 (307)

Breast Milk Donation After Perinatal Loss: A Qualitative Exploration of Maternal Grief and Healing Among Israeli Arab Women and the Islamic Legal-Ethical Perspectives: A Qualitative Research Study. [PDF]

Healthcare (Basel)
Tarabeih M, Yahya O, Sabbah M, Awawdi K.
europepmc   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression

Advanced Science, EarlyView.
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao, Yue Peng, Qing Liang, Shi Liu, Yang Li, Lei Ma, Menghan Hu, Sujuan Zheng, Zhihua Liu, Shugeng Gao   +9 more
wiley   +1 more source

Audit of pre-transfusion testing practices in hospital blood banks across Tanzania: A national survey. [PDF]

Afr J Lab Med
Mwashiuya OF, Lyimo MA, Mogela DJ, Bhombo AJ, Mwimo JL, Shewiyo EJ, Tingo BN.   +6 more
europepmc   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Racialized Black-White Economic Segregation and Major Chain Yoga Studio Locations in Major U.S. Metropolitan Areas. [PDF]

AJPM Focus
Xu KY, Ling R, Banks DE, Ku BS.
europepmc   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Visual Attention to Food Bank Posters: Insights from an Exploratory Eye-Tracking Study. [PDF]

Behav Sci (Basel)
Grabowska-Chenczke O, Rani A, Marek-Andrzejewska E, Kiryluk-Dryjska E.   +3 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source