Results 241 to 250 of about 2,357,768 (311)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Developing and Evaluating a Health Literacy Training Model for Volunteer Elderly Caregivers to Prevent and Control NCDs in Thailand: An Action Research Study. [PDF]

Nurs Rep
Boontem P, Phaitrakoon J, Jirarattanawanna N, Kanyamee M, Somboon S, Sanghirun K, Chulakarn N.   +6 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Teaching cornerball: a didactic proposal based on the sport education model. [PDF]

Front Sports Act Living
Diez-Fernández P, Rodríguez-Cayetano A, Gutiérrez-Gutiérrez S, Barcala-Furelos M, González-Gutiérrez I, Ruibal-Lista B, López-García S.   +6 more
europepmc   +1 more source

Barriers and Facilitators to Participation in Interventions for Employee Health and Wellbeing in the University Context. [PDF]

Stress Health
Bailey A, Kooij D, de Reuver R, Kupper N.   +3 more
europepmc   +1 more source

From prescription to practice: improving patient access and adherence to nature-based clinical interventions. [PDF]

Front Public Health
Heimlich-McQuarters M, Mouli SC, Lozada C, Dong W, Maddock JE, Al-Kindi S.   +5 more
europepmc   +1 more source

Self-Experienced Difficulties in Communicative Participation in Children With Speech, Language and Communication Needs-A Concept Elicitation Study. [PDF]

Int J Lang Commun Disord
Alons E, Berndsen-van Swaaij B, Terwee C, Gerrits E, Luinge M, Ewijk LV.   +5 more
europepmc   +1 more source

The importance of partnership in chronic pain - co-creation of tomorrow's pain care by working together in research, implementation, and knowledge dissemination. [PDF]

Front Pain Res (Lausanne)
Andréll P, Heckemann B, Grimby-Ekman A, Göran G, Olsson ML, Johansson R, Forslund P, Wolf A.   +7 more
europepmc   +1 more source

Manifestations of Boron-Alkali Metal and Boron-Alkaline-Earth Metal Romances. [PDF]

Acc Chem Res
Cui ZH, Cui LJ, Barroso J, Guo JC, Zhai HJ, Pan S, Merino G.   +6 more
europepmc   +1 more source