Results 41 to 50 of about 356,702 (245)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Reference Framework for E-participation Projects [PDF]
, 2011 Accommodating the various requirements from distinct perspectives in e-participation calls for a holistic engineering approach for e-participation systems analysis and design. This paper presents research results towards a reference framework for e-participation projects. An analysis of procedural models for e-participation and enterprise architectures
Scherer, Sabrina, Wimmer, Maria
openaire +1 more source
Rediscovering Community Participation in Persian Qanats: An Actor-Network Framework
European Journal of Creative Practices in Cities and Landscapes, 2019 Most of Iran's inland areas have permanently lain within arid regions. Today, Iran’s groundwater depletion-rate today among the fastest in the world.
Arash Salek
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
DIGITAL PARTICIPATION: MANAGEMENT AND LEGAL FRAMEWORK
European Cooperation, 2019 The paper explores the issues faced when shaping the legal framework for electronic democracy in Ukraine and management for further development. Special focus is on the pilot local and regional Concepts on e-democracy, and on digital participation developed in Vinnytsia, Dnipro, and Vinnytsia region.
Levchenko, Oleh +2 more
openaire +1 more source
Suspicious and fraudulent online survey participation: Introducing the REAL framework
Methodological Innovations, 2021 Online survey research has significantly increased in popularity in recent years. With its use, researchers have a new set of concerns about data collection and analysis to consider, including the possibility of fraudulent survey submissions. The purpose
Jennifer Lawlor +6 more
doaj +1 more source
Universal Journal of Educational Research, 2023 The Sangguniang Kabataan is an essential part of the government to develop the youth in the society and to encourage a meaningful youth participation in different sectors in the community.
Renniel Jayson Jacinto Rosales
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source